Results 61 to 70 of about 41,015 (284)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Modules Whose St-Closed Submodules are Fully Invariant

مجلة بغداد للعلوم
The duo module plays an important role in the module theory. Many researchers generalized this concept such as Ozcan AC, Hadi IMA and Ahmed MA. It is known that in a duo module, every submodule is fully invariant.
Maysaa Riadh Abbas, Muna Abbas Ahmed
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Purely Goldie Extending Modules

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
An -module  is extending if every submodule of   is essential in a direct summand of . Following Clark, an -module  is purely extending if every submodule of   is essential in a pure submodule of .
Saad A. Al-Saadi, Ikbal A. Omer
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The VISITOR Pattern as a Reusable, Generic, Type-Safe Component [PDF]

, 2008
The Visitor design pattern shows how to separate the structure of an object hierarchy from the behaviour of traversals over that hierarchy. The pattern is very flexible; this very flexibility makes it difficult to capture the pattern as anything more ...
Bruno C.d.S. Oliveira, Oliveira, BCDS, Oliveira, Bruno C D S, Oliveira, Bruno, Gibbons, J, Wang, M, Gibbons, Jeremy, Oliveira, Bruno César dos Santos, Meng Wang, Wang, Meng, Jeremy Gibbons   +10 more
core   +1 more source

Parametric L-systems-based modeling self-reconfiguration of modular robots in obstacle environments

International Journal of Advanced Robotic Systems, 2018
Self-reconfiguration of modular self-reconfigurable robots is a fundamental function that can be used as part of higher-level functionality. Interaction with the environment is a key factor affecting the self-reconfiguration process of modular robots. In
Dongyang Bie, Yulin Wang, Yu Zhang, Che Liu, Jie zhao, Yanhe Zhu   +5 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The T-extending condition relative to projection invariant submodules

, 2022
In this article, we investigate t-extending and t-Baer modules relative to projection invariant submodules. We introduce π-t-extending and π-t-Baer modules as a proper generalization of t-extending and t-Baer modules, respectively.
Tayyebeh Amouzegar, TERCAN, ADNAN, Adnan Tercan, Amouzegar, Tayyebeh   +3 more
core   +1 more source