Results 111 to 120 of about 41,015 (284)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Design and Improvement of an Automated Tool for Quality Control and Performance Assessment of Photovoltaic Modules

Solar
Photovoltaic (PV) systems are at the heart of the energy transition, providing an essential source of clean, renewable energy for applications such as solar pumping, which is essential for irrigation and rural water supply.
Alain Foutche Tchouli, Stephane Ndiya Ngasop, Jean Hilaire Tchami, Claude Bertin Nzoundja Fapi, Hyacinthe Tchakounté   +4 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

ON MONO-INJECTIVE MODULES AND MONO-OJECTIVE MODULES

, 2013
In [5] and [6], we have introduced a couple of relative generalized epi-projectivities and given several properties of these projectivities. In this paper, we consider relative generalized injectivities that are dual to these relative projectivities and ...
Keskin Tütüncü, Derya, Kuratomi, Yosuke   +1 more
core   +1 more source

Representation of 3D Land Cover Data in Semantic City Models

ISPRS International Journal of Geo-Information
A large number of cities have created semantic 3D city models, but these models are rarely used as input data for simulations, such as noise and flooding, in the urban planning process.
Per-Ola Olsson, Axel Andersson, Matthew Calvert, Axel Loreman, Erik Lökholm, Emma Martinsson, Karolina Pantazatou, Björn Svensson, Alex Spielhaupter, Maria Uggla, Lars Harrie   +10 more
doaj   +1 more source

Structuring of specification modules (extended)

Comput. Sci. J. Moldova, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Extending modules with injective or semisimple summands

, 1998
We characterize when the direct sum of an extending module and an injective module is extending and when the direct sum of an extending module with the finite exchange property and a semisimple module is extending.
Santa-Clara, Catarina
core   +1 more source