Results 101 to 110 of about 41,015 (284)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Journal of Algebra, 1981 An important part of Clifford’s theory does not work properly for arbitrary fields R. To see why, we must recall the main steps of this theory. We are interested in extensions to RH-modules of a fixed H-invariant irreducible RN-module a, where N is a normal subgroup of a finite group H. We first pass to the factor algebra ‘u = RH/3 modulo the ideal 3 =
openaire +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Dual Goldie and EC-complement Versions of the Extending Property
, 2016 Not ...
TERCAN, ADNAN +5 more
core +1 more source
IEEE AccessA household solar energy supply composed of photovoltaic (PV) modules and battery packs is proposed and analyzed for its feasibility and self-sustainability.
Xiang-Yi Wang, Jean-Fu Kiang
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Extending modules relative to module classes
, 1997 The purpose of this study is to give an up-to-date presentation of known and new results on extending modules and related notions with respect to an R-module class X. By assuming basic facts from Module Theory, our treatment is essentially self-contained.
Dogruoz, Semra, Dogruoz, S.
core +1 more source
Energy Science & EngineeringThis article proposes a composite fault‐tolerant control strategy combining zero‐mode control and half‐wave reconfiguration to address single IGBT open‐circuit faults in cascaded H‐bridge converters.
Lei Dong +5 more
doaj +1 more source