Results 71 to 80 of about 41,015 (284)

Equivalence of Almost N-Automorphism-Invariant and Almost N-Pseudo-Injective Modules

Journal of Mathematics
The objective of this work is to generalize a result of Fuchigami, Kuratomi, and Shibata, published in the Journal of Algebra and Its Applications, Vol. 23, No. 2, 24500272024.
Amnah A. Alkinani, Ahmad M. Alghamdi
doaj   +1 more source

Green Route for Fabrication of Water-Treatable Thermoelectric Generators

Energy Material Advances, 2022
Since future energy harvesting technologies require stable supply and high-efficiency energy conversion, there is an increasing demand for high-performance organic thermoelectric generators (TEGs) based on waterproof thermoelectric materials.
Shinichi Hata, Misaki Shiraishi, Soichiro Yasuda, Gergely Juhasz, Yukou Du, Yukihide Shiraishi, Naoki Toshima   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Dynamic rendering of the heterogeneous cell response to anticancer treatments. [PDF]

PLoS Computational Biology, 2013
The antiproliferative response to anticancer treatment is the result of concurrent responses in all cell cycle phases, extending over several cell generations, whose complexity is not captured by current methods.
Francesca Falcetta, Monica Lupi, Valentina Colombo, Paolo Ubezio   +3 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Assessing the Environmental Benefits of Extending the Service Lifetime of Solar Photovoltaic Modules

Global Challenges
Requiring no fuel for generation and negligible material/energy for operation and maintenance, photovoltaic (PV) systems have environmental impacts mostly due to the production of modules and the commissioning of power plants. Thus, extending the service
Ahmed Burak Paç, Abdulkerim Gok
doaj   +1 more source

Charging Characteristics of Lithium Ion Battery Using Semi-Solar Modules of Polymer:Fullerene Solar Cells

Energies, 2017
The combination of lithium ion battery (LIB) and organic (polymer) solar cells is expected to deliver versatile self-rechargeable portable energy sources, but less attention has been paid to the charging characteristics of LIB-using polymer solar cells ...
Myeonghun Song, Sooyong Lee, Dohan Kim, Chulyeon Lee, Jaehoon Jeong, Jooyeok Seo, Hwajeong Kim, Dong-Ik Song, Donghyun Kim, Youngkyoo Kim   +9 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source