Results 91 to 100 of about 2,301,565 (248)

Economic Development and the Quality of Life of Children [PDF]

open access: yes, 2004
Historical studies show that the average height of Western European children began its secular growth in 1850 only after a period of decline and stagnation which had started around 1750.
Delajara, Marcelo
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Oscar Jara Holliday: «La extensión es el motor de la relación universidad-sociedad»

open access: yesExtensión en Red, 2019
En esta entrevista, Oscar Jara Holliday da cuenta de qué es la sistematización de experiencias y cuál es la importancia de producir conocimiento sobre nuestras propias prácticas, desde una perspectiva teórico-política.
Luciana Isa   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Unificación y extensión jurisprudencial en el proceso administrativo [PDF]

open access: yes, 2014
La Ley 1437 de 2011 ofrece novedades en la normatividad que rige el funcionamiento de la administración pública, así como en los mecanismos y procedimientos con que cuentan los particulares para hacer uso efectiva de esta. Esos cambios en la legislación,
Castro Vargas, Paola Andrea   +1 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

La práctica pedagógica en el proceso de formación del abogado en Colombia

open access: yesEducación y Humanismo, 2015
Con esta publicación se pretende invitar a los facilitadores del proceso de formación del jurista a reflexionar en torno al siguiente interrogante: ¿la práctica pedagógica utilizada por el docente en el aula es pertinente para desarrollar las ...
Gladys Shirley Ramírez Villamizar   +1 more
doaj  

La UBA y la cultura [PDF]

open access: yes, 2008
Fil: García, Oscar Gabriel. Universidad de Buenos Aires.
García, Oscar Gabriel
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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