Results 91 to 100 of about 2,301,565 (248)
Economic Development and the Quality of Life of Children [PDF]
Historical studies show that the average height of Western European children began its secular growth in 1850 only after a period of decline and stagnation which had started around 1750.
Delajara, Marcelo
core +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Oscar Jara Holliday: «La extensión es el motor de la relación universidad-sociedad»
En esta entrevista, Oscar Jara Holliday da cuenta de qué es la sistematización de experiencias y cuál es la importancia de producir conocimiento sobre nuestras propias prácticas, desde una perspectiva teórico-política.
Luciana Isa +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Unificación y extensión jurisprudencial en el proceso administrativo [PDF]
La Ley 1437 de 2011 ofrece novedades en la normatividad que rige el funcionamiento de la administración pública, así como en los mecanismos y procedimientos con que cuentan los particulares para hacer uso efectiva de esta. Esos cambios en la legislación,
Castro Vargas, Paola Andrea +1 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
La práctica pedagógica en el proceso de formación del abogado en Colombia
Con esta publicación se pretende invitar a los facilitadores del proceso de formación del jurista a reflexionar en torno al siguiente interrogante: ¿la práctica pedagógica utilizada por el docente en el aula es pertinente para desarrollar las ...
Gladys Shirley Ramírez Villamizar +1 more
doaj
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

