Results 81 to 90 of about 206,308 (195)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Curricularización de la extensión universitaria: prácticas y sentidos en disputa
, 2018 La curricularización de la extensión no resulta un hecho aislado dentro de las derivas extensionistas. Ésta se ve fortalecida por dos políticas convergentes: por un lado, un proceso de integración de las funciones universitarias (enseñanza, extensión e ...
Extensión, Secretaría de
core
, 2018 El presente artículo propone reflexionar acerca de los recorridos y desafíos que ha enfrentado y enfrenta la extensión universitaria como función sustantiva de las instituciones de educación superior de gestión pública. Este tránsito es continuo y fluido,
Itoiz, Juan Pablo, Juan Pablo Itoiz
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Methodology for competitive association and quality management in Ecuadorian pymes
Cooperativismo y Desarrollo, 2019 Small and medium-sized companies to which the literature has paid scant attention to date, but which nevertheless represent a high percentage of gross domestic product, and accumulate a large part of the employment generated in the main economies of the ...
Verónica Cecilia Cabrera González +1 more
doaj
, 2018 O texto apresenta uma breve síntese do que é a extensão, projeção social ou articulação como função universitária, a fim de compreender o papel desempenhado pelas redes acadêmico-universitárias como mecanismos de cooperação.
Valenzuela Tovar, Sylvia María
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
La imprescriptibilidad de la masacre de Aztra, crimen de lesa humanidad
Perspectivas, 2019 El presente trabajo pretende aclarar si el horrendo crimen que se perpetró el 18 de octubre de 1977, época en la que existía el Gobierno de facto, estaría catalogado como un crimen de lesa humanidad.
Julio César Gárate Amoroso +2 more
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
INTERDISCIPLINA EN TENSIÓN: UNA PRÁCTICA DE EDUCACIÓN FÍSICA
Revista Tempos e Espaços em Educação, 2019 En el siguiente trabajo nos proponemos analizar e1 proceso desarrollado en el marco del acuerdo EFI del 2014. Particularmente, nos centraremos en visibilizar y analizar la dimensión inter y transdiciplinaria del proyecto y las tensiones que se presentan ...
Martín Caldeiro, Camilo Rodríguez
doaj +1 more source