Results 71 to 80 of about 1,516,048 (285)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Institutional Theory of M. Olson: «The Principle of Expansion» [PDF]
Журнал институциональных исследований, 2017 The article explores the basic concepts of Mancur Olson's special interest groups theory, which demonstrates the «logic of collective action», elaborated using John Commons’ «extension principle».
Sukharev Oleg S.
doaj +1 more source
Basic principles of the genetic code extension [PDF]
Royal Society Open Science, 2019 AbstractCompounds including non-canonical amino acids or other artificially designed molecules can find a lot of applications in medicine, industry and biotechnology. They can be produced thanks to the modification or extension of the standard genetic code (SGC).
Paweł Błażej +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Consistent Extension of Condorcet’s Election Principle [PDF]
SIAM Journal on Applied Mathematics, 1978 Condorcet's principle of choosing the majority alternative whenever one exists is violated not only by Borda's rule but also by any scoring method; nevertheless, the essential property of scoring functions -- "consistency" of the outcome under aggregation of subgroups -- is shown to be compatible with Condorcet's principle.
Young, H. P., Levenglick, A.
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Martelli Chaotic Properties of a Generalized Form of Zadeh’s Extension Principle
Journal of Applied Mathematics, 2014 Let X denote a compact metric space and let f : X→X be a continuous map. It is known that a discrete dynamical system (X,f) naturally induces its fuzzified counterpart, that is, a discrete dynamical system on the space of fuzzy compact subsets of X.
Yaoyao Lan, Chunlai Mu
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Гений oртопедии, 2021 The understanding of Ilizarov’s biological principles is guiding clinical treatment. Ilizarov’s First Principle of Biology, Distraction Histogenesis, is a fundamental guidance for bone lengthening.
Weiwei Chen, Long Qu
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Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Solving Fuzzy Multiproduct Aggregate Production Planning Problems Based on Extension Principle
International Journal of Mathematics and Mathematical Sciences, 2014 Aggregate production planning (APP) plays a critical role in supply chain management (SCM). This paper investigates multiproduct, multiperiod APP problems with several distinct types of fuzzy uncertainties.
Shih-Pin Chen, Wen-Lung Huang
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