Results 71 to 80 of about 175,766 (297)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Friedrichs Extension and Min–Max Principle for Operators with a Gap
, 2019 Semibounded symmetric operators have a distinguished self-adjoint extension, the Friedrichs extension. The eigenvalues of the Friedrichs extension are given by a variational principle that involves only the domain of the symmetric operator.
Lukas Schimmer +8 more
core +2 more sources
Fractal-pyramid fractance approximation circuit—scaling extension and optimization design principle
四川大学学报. 自然科学版, 2021 Analyze the characteristics of B-type fractal-pyramid fractance approximation circuit, which has only negative half-order operational performance. According to scalingextension theory, a fractance approximation circuit with arbitrary real-order calculus ...
ZHANG Yue-Rong, GUO Zhao-Ru, YUAN Xiao
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Control diseases for finer tomatoes
, 1960 Describes the most common diseases of tomatoes and lists principle control measures ...
Fenne, S.B.
core
The unitary extension principle for locally compact abelian groups with co-compact subgroups
, 2021 The unitary extension principle by Ron and Shen is one of the cornerstones of wavelet frame theory; it leads to tight frames for L2(R) and associated expansions of functions f ∈ L2(R) of similar type as those for orthonormal wavelet bases. In this paper,
Christensen, Ole, Goh, Say Song
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Solving Fuzzy Multiproduct Aggregate Production Planning Problems Based on Extension Principle
International Journal of Mathematics and Mathematical Sciences, 2014 Aggregate production planning (APP) plays a critical role in supply chain management (SCM). This paper investigates multiproduct, multiperiod APP problems with several distinct types of fuzzy uncertainties.
Shih-Pin Chen, Wen-Lung Huang
doaj +1 more source
Agricultural extension - generic challenges and the ingredients for solutions [PDF]
Is agricultural extension in developing countries up to the task of providing the information, ideas, and organization needed to meet food needs? What role should governments play in implementing or facilitating extension services?
Feder, Gershon +2 more
core