Results 71 to 80 of about 5,663,167 (335)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
The Fujita exponent for semilinear heat equations with quadratically decaying potential or in an exterior domain [PDF]
, 2008 Consider the equation (0.1)ut=Δu−Vu+aupin Rn×(0,T);u(x,0)=ϕ(x)≩0in Rn, where p>1, n⩾2, T∈(0,∞], V(x)∼ω|x|2 as |x|→∞, for some ω≠0, and a(x) is on the order |x|m as |x|→∞, for some m∈(−∞,∞).
R. Pinsky
semanticscholar +1 more source
A Nonlinear Parabolic Problem in an Exterior Domain
Journal of Differential Equations, 1998 The author considers the parabolic differential equation \(u_t -\Delta u +u^p=0\) in the exterior of a bounded domain with finitely many components, each having a smooth boundary. Zero Dirichlet data is prescribed along with an initial function \(u_0\) such that \[ \lim_{| x| \to\infty} \frac {u^0(x)}{A| x| ^{-\alpha}} = 1 \] for some positive ...
openaire +2 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
, 1974 Copia digital. España : Ministerio de Cultura y Deporte.
Comisiones Obreras. Delegación Exterior
core +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
On the Wiener criterion in higher dimensions
Boundary Value Problems, 2017 The Wiener criterion is a sufficient and necessary condition for the solvability of the Dirichlet problem. However, its geometric interpretation is not clear.
Tariq Ismaeel
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
A importância do MERCOSUL para o comércio exterior brasileiro [PDF]
, 2014 TCC (graduação) - Universidade Federal de Santa Catarina. Centro Sócio-Econômico. Economia.O presente trabalho apresenta análise do Comércio Exterior Brasileiro, dando importância para o MERCOSUL nesses últimos anos.
Fernandes, Herlon
core
Energy integral of the Stokes flow in a singularly perturbed exterior domain [PDF]
Opuscula Mathematica, 2012 We consider a pair of domains \(\Omega ^b\) and \(\Omega ^s\) in \(\mathbb{R}^n\) and we assume that the closure of \(\Omega ^b\) does not intersect the closure of \(\epsilon \Omega ^s\) for \(\epsilon \in (0,\epsilon _0)\).
Matteo Dalla Riva
doaj +1 more source