Results 41 to 50 of about 16,079 (267)
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Existence of solutions for semilinear problems with prescribed number of zeros on exterior domains
In this article we prove the existence of an infinite number of radial solutions of $\Delta(u)+f(u)=0$ with prescribed number of zeros on the exterior of the ball of radius R>0 centered at the origin in $\mathbb {R}^N$ where f is odd with f0 on ...
Janak Joshi, Joseph Iaia
doaj
We are concerned with the radial solutions of the Dirichlet problem $-\Delta u=K(|x|)f(u)$ on the exterior of the ball of radius $R>0$ centered at the origin in $\mathbb{R}^N \text{ with } N\geq 3$ where $f$ is superlinear at $\infty$ and has a ...
Narayan Aryal, Joseph Iaia
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Hessian equations on exterior domain
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Cao, Xu, Bao, Jiguang
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Stationary solutions for generalized Boussinesq models in exterior domains
We establish the existence of a stationary weak solution of a generalized Boussinesq model for thermally driven convection in exterior domains. Namely, it is expected that the exterior domain can be approximated by interior domains.
E.A. Notte-Cuello, M.A. Rojas-Medar
doaj
Blow-Up Results for Higher-Order Evolution Differential Inequalities in Exterior Domains
We consider a higher-order evolution differential inequality in an exterior domain of ℝN{\mathbb{R}^{N}}, N≥3{N\geq 3}, with Dirichlet and Neumann boundary conditions.
Jleli Mohamed +2 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Some remarks on Riesz transforms on exterior Lipschitz domains
Let $n\ge 2$ and $\mathcal {L}=-\mathrm {div}(A\nabla \cdot )$ be an elliptic operator on $\mathbb {R}^n$ . Given an exterior Lipschitz domain $\Omega $ , let $\mathcal {L}_D$ be the elliptic operator $\mathcal {L}$
Renjin Jiang, Sibei Yang
doaj +1 more source

