Results 101 to 110 of about 4,429,440 (301)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Feature Story: Training and teamwork help save a life
, 2014 One person is alive today thanks to a quick response from people who were at the right place at the right time at the University of Regina. The person, who does not want to be identified, collapsed while working out at the U of R’s Fitness and Wellness ...
External Relations, University of Regina
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Product market competition, external economies of scale and unionized wage [PDF]
Although empirical evidence shows that higher product market competition increases unionized wage, the theoretical literature did not pay much attention to this aspect.
Arijit Mukherjee
core
MusclesGiven the posterior chain configuration, it is anticipated that tibial positioning influences hamstring recruitment; medial hamstrings should be more activated during medial rotation, while lateral hamstrings should be more activated during lateral ...
Ricardo Maia Ferreira +5 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
, 1978 Part of the collection of government and miscellaneous documents relating to the history of ...
Canada. Department of External Affairs
core +1 more source
External debt, economic growth and investment in Egypt, Morocco and Tunisia [PDF]
Most developing countries are dependent on external borrowing to achieve economic growth. However, external borrowing requires fixed payments independent of the actual return on the invested funds.
Abuzaid, Lotfi Elhadi Mohamed
core +3 more sources