Results 91 to 100 of about 4,429,440 (301)

A Global Perspective on External Positions [PDF]

open access: yes
The paper highlights the increased dispersion in net external positions in recent years, particularly among industrial countries. It provides a simple accounting framework that disentangles the factors driving the accumulation of external assets and ...
Gian Maria Milesi-Ferreti, Philip Lane
core   +2 more sources

SELF-DIRECTED LEARNING USING THE QUADRIPARTITE CYCLEOF STRUCTURATION – A DESCRIPTIVE CASE STUDY

open access: yesMalaysian Journal of Learning and Instruction
Purpose – The purpose of this study is to explore how the internal elements and external conditions of learners shape their Self-Directed Learning (SDL).
Chai Ping Woon, Meng Yew Tee
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Does Military Spending Explode External Debt in Pakistan? [PDF]

open access: yes
This paper explores the effect of military expenditures on external debt in case of Pakistan over the period of 1973-2009. For this purpose, ARDL bounds testing approach is used to examine cointegration between the variables.
Butt, Muhammad Sabihuddin   +2 more
core  

External auditory canal osteoma [PDF]

open access: yes, 2020
Left ear pain. Otoscopy shows left external auditory canal hard mass obscuring view. There is a small pedunculated well-corticated bony outgrowth within the left external acoustic meatus.
Abidin, Mohd Radhwan
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Financial remoteness and the net external position [PDF]

open access: yes
This paper shows that, controlling for standard determinants of net external positions, financially-remote countries exhibit more positive net external positions.
Schmitz, Martin
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

External Debt and Liabilities of Industrial Countries [PDF]

open access: yes
This paper attempts to overcome the lack of comparable data on the external indebtedness of the industrial countries by constructing consistent time series of data on external debt and the overall international investment position of these countries.
Mark Rider
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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