Results 71 to 80 of about 2,405,589 (265)

Design and research of high sensitive GIS intermittent partial discharge leakage electromagnetic wave detection sensor

Diance yu yibiao
Aiming at the requirement of highly sensitive perception of gas insulated switchgear (GIS) intermittent partial discharge leakage electromagnetic wave.
QIU Hu, YANG Xu, LUO Chuanxian, ZHANG Jing, WEN Hao, ZHANG Guozhi   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Anatomia microcirúrgica da artéria carótida externa: um estudo estereoscópico Microsurgical anatomy of the external carotid artery: a stereoscopic study

Jornal Vascular Brasileiro, 2012
CONTEXTO: O conhecimento das estruturas anatômicas da artéria carótida externa por meio do estudo estereoscópico pode determinar melhores resultados em microcirurgias da artéria carótida externa.
Gustavo Rassier Isolan, Adamastor Humberto Pereira, Paulo Henrique Pires de Aguiar, Ápio Cláudio Martins Antunes, João Pedro Mousquer, Marcel Rozin Pierobon   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

COMPARISON OF MEAN DASH SCORE AFTER CLOSE REDUCTION AND EXTERNAL FIXATION VERSUS OPEN REDUCTION INTERNAL FIXATION (ORIF) WITH PLATING FOR TREATING INTRA-ARTICULAR FRACTURE OF DISTAL RADIUS

Journal of University Medical & Dental College, 2018
: OBJECTIVE: To compare the mean DASH score after close reduction and external fixation versus ORIF with plating for treating intra-articular fracture of distal radius.
Zulfiqar Ahmad , Mueed Ahmad, Hayyan Ahmad   +2 more
doaj  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

SELF-DIRECTED LEARNING USING THE QUADRIPARTITE CYCLEOF STRUCTURATION – A DESCRIPTIVE CASE STUDY

Malaysian Journal of Learning and Instruction
Purpose – The purpose of this study is to explore how the internal elements and external conditions of learners shape their Self-Directed Learning (SDL).
Chai Ping Woon, Meng Yew Tee
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source