Results 131 to 140 of about 2,957,278 (289)

Evaluation of Concordance between Radiation Therapists and Medical Physicists in MR‐Guided Online Adaptive Planning

open access: yesPrecision Radiation Oncology, EarlyView.
Magnetic resonance (MR)‐guided online adaptive radiotherapy requires skill in online adaptive treatment planning. This study demonstrated that radiation therapists, with appropriate training, can consistently produce high‐quality adaptive plans concordant with those created by medical physicists for treatment on a 1.5 Tesla MR‐Linac.
Eva Birring   +10 more
wiley   +1 more source

Stereotactic Prostate Cancer Ablative Re‐Irradiation: A Systematic Review and Meta‐Analysis (SPARE)

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Stereotactic ablative radiotherapy (SABR) is emerging as an alternative treatment for patients with locally recurrent prostate cancer after previous radiation. This approach allows for precise target coverage while limiting toxicity to surrounding organs.
Andre G. Gouveia   +12 more
wiley   +1 more source

Prognostic Value of MRI‐Derived Apparent Diffusion Coefficient in Intermediate‐Risk Prostate Cancer Treated With Definitive Radiotherapy

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Intermediate‐risk prostate cancer (IR‐PCa) is a heterogeneous disease with variable clinical outcomes despite established risk classification. We evaluated whether pretreatment tumor apparent diffusion coefficient (ADC) derived from multiparametric MRI was associated with long‐term outcomes and provided additional prognostic ...
Cem Onal   +4 more
wiley   +1 more source

Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy

open access: yesPhytotherapy Research, EarlyView.
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi   +9 more
wiley   +1 more source

Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists

open access: yesSmartBot, EarlyView.
Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu   +12 more
wiley   +1 more source

Context‐Dependent Radioenhancement by Platinum Nanoparticles Under Conventional and Ultra‐High Dose‐Rate “FLASH” Radiotherapy

open access: yesSmall, EarlyView.
Overview of the experimental workflow and main findings of the study investigating Pt‐NPs‐mediated radioenhancement under conventional 134 dose‐rate (CONV) and ultrahigh dose‐rate (UHDR) 9 MeV electron irradiation. Pt‐NP distribution and uptake were characterized in 4T1 spheroids and syngeneic tumor models.
Cathyanne Schott   +14 more
wiley   +1 more source

Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments

open access: yesSmart Molecules, EarlyView.
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu   +7 more
wiley   +1 more source

External beam radiotherapy synergizes 188Re-liposome against human esophageal cancer xenograft and modulates 188Re-liposome pharmacokinetics

open access: yes, 2015
Chih-Hsien Chang,1,2 Shin-Yi Liu,3 Chih-Wen Chi,3 Hsiang-Lin Yu,1 Tsui-Jung Chang,1 Tung-Hu Tsai,4 Te-Wei Lee,1 Yu-Jen Chen3–5 1Isotope Application Division, Institute of Nuclear Energy Research, Taoyuan, Taiwan; 2Department of Biomedical Imaging ...
Tsai TH   +7 more
core  

Boron‐embedded multifunctional nanoplatform toward potential combined boron neutron capture therapy and immunomodulation in glioma

open access: yesSmart Molecules, EarlyView.
A brain‐targeting multifunctional nanoplatform (DM&Ce6@COF‐Ang) was engineered by employing boron‐enriched APTES‐COF‐1 as both the therapeutic boron agent and the nanocarrier co‐delivery of DMXAA and Ce6. This nanoplatform achieved synergistic tumor‐specific boron delivery, real‐time pharmacokinetic monitoring, and immunomodulation.
Yiming Liu   +13 more
wiley   +1 more source

Reducing unnecessary osteoporosis treatment in prostate cancer with FRAX‐BMD integration

open access: yesUroPrecision, EarlyView.
ABSTRACT Background Men on androgen deprivation therapy (ADT) for prostate cancer frequently develop osteoporosis, and up to 20% fracture within five years. The Fracture Risk Assessment Tool (FRAX) estimates 10‐year fracture probability with or without bone mineral density (BMD), but data in this population are scarce.
Takashi Kawahara   +10 more
wiley   +1 more source

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