Results 141 to 150 of about 2,620,097 (300)

Assessment of incompleteness of Mortality Information System records on deaths from external causes in the state of Rio Grande do Sul, Brazil, 2000-2019. [PDF]

Epidemiol Serv Saude, 2023
Barbosa JS, Tartaro L, Vasconcelos LDR, Nedel M, Serafini JF, Svirski SGS, Souza LS, Agranonik M.   +7 more
europepmc   +1 more source

An Unusual Cause of Hemiplegia: External Hydrocephalus [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2009
Ralph, Rahme, Ronald, Moussa, Lina, Menassa-Moussa, Elie, Samaha   +3 more
openaire   +2 more sources

The Benefits of Believing in Chance or Fate: External Locus of Control as a Protective Factor for Coping with the Death of a Spouse [PDF]

The death of a spouse is an extremely stressful life event that consequently causes a large drop in life satisfaction. Reactivity to the loss, however, varies markedly, a phenomenon that is currently not well understood.
Boris Egloff, Jule Specht, Stefan C. Schmukle   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Parental death by external causes and risk of hospital-treated deliberate self-harm in bereaved offspring. [PDF]

Eur Child Adolesc Psychiatry, 2021
Burrell LV, Mehlum L, Qin P.
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Racial and Ethnic Disparities in Estimated Excess Mortality From External Causes in the US, March to December 2020.

JAMA Intern Med, 2022
Chen R, Aschmann HE, Chen YH, Glymour MM, Bibbins-Domingo K, Stokes AC, Kiang MV.   +6 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Onset of mortality increase with age and age trajectories of mortality from all diseases in the four Nordic countries

Clinical Interventions in Aging, 2017
Josef Dolejs,1 Petra Marešová2 1Department of Informatics and Quantitative Methods, 2Department of Economics, Faculty of Informatics and Management, University of Hradec Králové, Hradec Králové, Czech Republic ...
Dolejs J, Marešová P
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