Results 71 to 80 of about 2,635,035 (294)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Morbidity due to External Causes among youngsters in an area of the municipality of Porto Alegre-RS

open access: yesOnline Brazilian Journal of Nursing, 2006
This study aims at learning and understanding the morbidity due to External Causes among youngsters, considering the demand for health care services in the Area of Lomba do Pinheiro and Partenon in the municipality of Porto Alegre – RS over the time ...
Marta Cocco, Marta Julia Marques Lopes
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

FACTORS ASSOCIATED TO MORTALITY IN HOSPITALIZED PATIENTS DUE TO EXTERNAL CAUSES

open access: yesCogitare Enfermagem, 2019
Objective: To analyze the factors associated to mortality in hospitalized patients due to external causes, according to the characteristics of the individuals, the injuries and hospitalizations.Method: Cross-sectional study based on secondary data from ...
Vanessa Almeida Cardoso Silva   +6 more
doaj   +1 more source

External labor migration from Ukraine: causes, scale, consequences

open access: yesEuropean Journal of Management Issues, 2019
Purpose – to study the causes and consequences of migration processes. The results of the study. This article presents the results of an analysis of the dynamics and current state of labor migration processes in Ukraine.
Viktoria Apalkova, Anna Lyzunova
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Central Asia: Problems of External Debt and Its Sustainability [PDF]

open access: yes
This paper is devoted to one of the most urgent problems of Central Asian economies in transition, i.e. external debt and its sustainability within systemic transformation process.
Islamov, Bakhtior
core  

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