Results 81 to 90 of about 693,569 (261)

Childhood deaths from external causes in Estonia, 2001–2005

open access: yesBMC Public Health, 2007
Background In 2000, the overall rate of injury deaths in children aged 0–14 was 28.7 per 100000 in Estonia, which is more than 5 times higher than the corresponding rate in neighbouring Finland.
Soonets Ruth   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Violência e morte: diferenciais da mortalidade por causas externas no espaço urbano do Recife, 1991

open access: yesCadernos de Saúde Pública
Este estudo teve como objetivo descrever a tendência e a magnitude das mortes violentas na cidade do Recife, sua distribuição espacial no ano de 1991 e seus diferenciais quanto ao sexo, idade, local de ocorrência; objetivou, também, analisar a ...
Maria Luiza C. de Lima, Ricardo Ximenes
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An Unusual Cause of Hemiplegia: External Hydrocephalus [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2009
Ralph, Rahme   +3 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Utilização da imprensa escrita na qualificação das causas externas de morte

open access: yesRevista de Saúde Pública
OBJETIVO: Complementar a informação sobre a causa básica de morte em óbitos por causas externas com uso de notícias veiculadas em jornais. MÉTODOS: Estudo de investigação de 153 óbitos por causas externas ocorridas em residentes de Belo Horizonte, MG, em
Lenice de Castro Mendes Villela   +4 more
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Mortalidad por causas accidentales en niños menores de 5 años en el Hospital Nacional de Niños "Dr. Carlos Sáenz Herrera", 2002-2004 Mortality due to accidental causes in children younger than 5 years of age at the Hospital Nacional de Niños "Dr. Carlos Sáenz Herrera", 2002-2004

open access: yesActa Médica Costarricense, 2008
Las lesiones traumáticas por causas externas corresponden en Costa Rica a la segunda causa de muerte en niños menores de 5 años, con una tasa para 2004 de 9.23 x 100000 habitantes, y la primera causa de años de vida potencialmente perdidos (37%) para ...
Adriana Benavides-Lara   +1 more
doaj  

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