Results 101 to 110 of about 796,634 (314)

Modeling Turbulent Flow in Stirred Tanks with CFD: The Influence of the Modeling Approach, Turbulence Model and Numerical Scheme [PDF]

, 2004
Single phase turbulent flow in a tank stirred by a down- and an up-pumping pitched blade turbine has been simulated using CFD. The effect of the modeling approach, discretization scheme and turbulence model on mean velocities, turbulent kinetic energy ...
Fletcher, David F., Aubin, Joelle, Xuereb, Catherine   +2 more
core   +1 more source

An Experimental Investigation on the Energy Signature Associated With Multiphase Flow in Porous Media Displacement Regimes

Water Resources Research
This study investigates the energy signature associated with multiphase flow in porous media displacement regimes. We proposed that net efficiency, as the conversion of external work applied to surface energy generated, provides new insights into the ...
Shuangmei Zou, Dong Chen, Nong Kang, Congjiao Xie, Ryan T. Armstrong, Jianchao Cai   +5 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Internal financial constraints, external financial constraints, and investment choice: Evidence from a panel of UK firms [PDF]

This paper uses a panel of 24184 UK firms over the period 1993-2003 to study the extent to which the sensitivity of investment to cash flow differs at firms facing different levels of internal and external financial constraints.
Alessandra Guariglia
core  

Dynamic Response Analysis of a Subsea Rigid M-Shaped Jumper under Combined Internal and External Flows

Journal of Marine Science and Engineering
To analyze the dynamic response of a rigid M-shaped jumper subjected to combined internal and external flows, a one-way coupled fluid–structure interaction process is applied.
Guangzhao Li, Wenhua Li, Shanying Lin, Fenghui Han, Xingkun Zhou   +4 more
doaj   +1 more source

The flow structure in a three-dimensional Model of abdominal aortic bifurcation: ultrasonic and numerical study

St. Petersburg Polytechnical University Journal: Physics and Mathematics, 2019
A numerical and experimental research of fluid flow structure on a model involving statistical-average bifurcations of the abdominal aorta and iliac arteries with an axisymmetric stenosis in the right common iliac artery has been conducted.
Sinitsyna Daria, Yukhnev Andrey, Zaitsev Dmitrii, Turkina Maria   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

The external validity of published randomized controlled trials in primary care [PDF]

, 2009
Background - A criticism of Randomized Controlled Trials (RCTs) in primary care is that they lack external validity, participants being unrepresentative of the wider population.
Jones Robert O, McCowan, Colin, Jones, R, Colin McCowan (434192), McCowan, C, Fahey, T., Jones, Robert O., Colin McCowan, Montgomery, AA, Fahey Tom, Jones, RO, Fahey, T, McCowan Colin, Alan A Montgomery, Montgomery Alan A, Jones Ritu, Fahey, Thomas, Robert O Jones, Ritu Jones (7944167), Tom Fahey (7896266), Robert O. Jones (7944170), Alan A. Montgomery (7705694), Tom Fahey, Ritu Jones, Mccowan, C., Montgomery, A.A., Jones, R.O., Montgomery, Alan A., Jones, R., Jones, Ritu   +29 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Does the Investment Opportunities Bias Affect the Investment-Cash Flow Sensitivities of Unlisted SMEs? [PDF]

Using a panel of 5,999 small and medium-sized Belgian enterprises (SMEs) over the period 2002-2008, we identify three measures of investment opportunities suitable for unlisted firms. We then estimate firm-varying investment-cash flow sensitivities (ICFS)
Bert D’Espallier, Alessandra Guariglia
core