Results 51 to 60 of about 3,220,539 (261)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Evaluation of n-alkanes and their carbon isotope enrichments (d13C) as diet composition markers [PDF]

open access: yes, 2011
Plant cuticular n-alkanes have been successfully used as markers to estimate diet composition and intake of grazing herbivores. However, additional markers may be required under grazing conditions in botanically diverse vegetation.
Derseh, M.B.   +7 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Automatic Identification and Classification of Topical Discourse Markers [PDF]

open access: yesJisuanji kexue
Discourse markers,a kind of linguistic markers at the pragmatic level which have functions of organizing discourse,guiding signifier,and expressing emotions,have attracted extensive attention in linguistics.The accurate identification of discourse ...
YANG Jincai, YU Moyang, HU Man, XIAO Ming
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

External validation of anti-Müllerian hormone based prediction of live birth in assisted conception [PDF]

open access: yes, 2013
<p>Background - Chronological age and oocyte yield are independent determinants of live birth in assisted conception. Anti-Müllerian hormone (AMH) is strongly associated with oocyte yield after controlled ovarian stimulation.
Grisendi, V.   +6 more
core   +2 more sources

Prediction of response to pemetrexed in non-small-cell lung cancer with immunohistochemical phenotyping based on gene expression profiles

open access: yesBMC Cancer, 2019
Background Palliative pemetrexed-based chemotherapy remains a standard of care treatment for the majority of patients with advanced non-squamous non-small-cell lung cancer (NSCLC).
S. Visser   +7 more
doaj   +1 more source

Candidate gene biodosimetry markers of exposure to external ionizing radiation in human blood: A systematic review. [PDF]

open access: yesPLoS ONE, 2018
PurposeTo compile a list of genes that have been reported to be affected by external ionizing radiation (IR) and to assess their performance as candidate biomarkers for individual human radiation dosimetry.MethodsEligible studies were identified through ...
Jerome Lacombe   +3 more
doaj   +1 more source

Designable visual markers [PDF]

open access: yes, 2009
Visual markers are graphic symbols designed to be easily recognised by machines. They are traditionally used to track goods, but there is increasing interest in their application to mobile HCI. By scanning a visual marker through a camera phone users can
Costanza, Enrico   +3 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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