Results 61 to 70 of about 3,220,539 (261)

Investigation on Performance Accuracy of Different Surrogates in Real Time Tumor Tracking at External Beam Radiotherapy

Frontiers in Biomedical Technologies, 2015
Purpose: In external beam radiotherapy of dynamic tumors, several errors raise due to inter- and intra-fractional motions. In order to compensate these errors, signals obtained from different surrogates are used to infer with tumor motion as real time ...
Saber Nankali, Ahmad Esmaili Torshabi, Payam Samadi-Miandoab, Amin Baghizadeh   +3 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

AI models predicting breast cancer distant metastasis using LightGBM with clinical blood markers and ultrasound maximum diameter

Scientific Reports
Breast cancer metastasis significantly impacts women's health globally. This study aimed to construct predictive models using clinical blood markers and ultrasound data to predict distant metastasis in breast cancer patients, ensuring clinical ...
Yang Tan, Wen-hai Zhang, Zhen Huang, Qi-xing Tan, Yue-mei Zhang, Chang-yuan Wei, Zhen-Bo Feng   +6 more
doaj   +1 more source

FONZIE: An optimized pipeline for minisatellite marker discovery and primer design from large sequence data sets

BMC Research Notes, 2010
Background Micro-and minisatellites are among the most powerful genetic markers known to date. They have been used as tools for a large number of applications ranging from gene mapping to phylogenetic studies and isolate typing.
Balesdent Marie-Hélène, Rouxel Thierry, Grandaubert Jonathan, Bally Pascal   +3 more
doaj   +1 more source

Severity-associated markers and assessment model for predicting the severity of COVID-19: a retrospective study in Hangzhou, China

BMC Infectious Diseases, 2021
Background The severity of COVID-19 associates with the clinical decision making and the prognosis of COVID-19 patients, therefore, early identification of patients who are likely to develop severe or critical COVID-19 is critical in clinical practice ...
Jianjiang Qi, Di He, Dagan Yang, Mengyan Wang, Wenjun Ma, Huaizhong Cui, Fei Ye, Fei Wang, Jinjian Xu, Zhijian Li, Chuntao Liu, Jing Wu, Kexin Qi, Rui Wu, Jinsong Huang, Shourong Liu, Yimin Zhu   +16 more
doaj   +1 more source

The Correlation Between Internal & External Markers for Abdominal Tumors: Implications for Respiratory Gating [PDF]

, 2005
Purpose: The correlation of the respiratory motion of external patient markers and abdominal tumors was examined. Data of this type are important for image-guided therapy techniques, such as respiratory gating, that monitor the movement of external ...
Brewer, Johanna, Betke, Margrit, Willett, Christopher G., Chen, George T.Y., Sharp, Gregory C., Gierga, David P.   +5 more
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Systemic inflammatory and stress markers in cattle and sheep submitted to different reproductive procedures

Ciência Rural, 2018
: Previous studies have evaluated the effects of different reproductive procedures on discomfort markers in sheep and cattle. Such studies may help stimulate the adoption of techniques that are more beneficial for animal welfare.
Vitória Gasperin Guazzelli Costa, Arnaldo Diniz Vieira, Augusto Schneider, Monique Tomazele Rovani, Paulo Bayard Dias Gonçalves, Bernardo Garziera Gasperin   +5 more
doaj   +1 more source

Predictive value of absolute CD4 cell count for disease progression in untreated HIV-1-infected children.

, 2006
OBJECTIVES: To describe the relationship between absolute CD4 cell count and the short-term risk of disease progression in HIV-1-infected children. DESIGN: A meta-analysis of individual longitudinal data on HIV-1-infected children enrolled in trials and ...
Partecipants, CONSOLINI, RITA, HIV Paediatric Prognostic Markers Collaborative Study   +2 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source