Results 91 to 100 of about 2,622,370 (297)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Distribution laws and effects analysis of casing external pressure taking elastic parameters matching into account

open access: yesPetroleum, 2016
Distribution laws of casing external pressure, which are obtained by different scholars in different conditions, are not the same. Thus, a model to calculate the external pressure of casing is established with finite element method.
Hongkun Zhang   +4 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Stability of a Filled Cylindrical Shell Strengthened by a Cross System of Ribs under Action of Different Loads Alternative in Time

open access: yesМеханика машин, механизмов и материалов, 2009
The consider dynamical stability problems for a closed, medium-filled cylindrical shell simply supported by end faces and strengthened by a cross system of ribs, under axial compression and uniform external pressure.
R.A. Iskenderov
doaj  

Pengaruh ROA, Proporsi Dewan Komisaris Independen, ACHANGE, LEV, DCHANGE Terhadap Tax Avoidance

open access: yesDisclosure
The background to this research focuses on several companies that carry out deliberate tax avoidance actions such as not remitting taxes that have been collected by not submitting Tax Returns (SPT). Tax avoidance or tax avoidance is an activity to reduce
Hesti Rahayu   +4 more
doaj   +1 more source

Subsea FRP pipeline performance in external pressure: Failure and external pressure-induced buckling

open access: yesIOP Conference Series: Materials Science and Engineering, 2021
Abstract The Subsea pipelines are subjected to high hoop stresses due to the hydrostatic pressure. When the internal pressure of the liquid has a higher value than the external hydrostatic one, there is a balance of the tensile and compressive stresses.
openaire   +2 more sources

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Buckling Strength and Sealing Performance of External Pressure-Resistant Stiffened Cylindrical Shell Structures with Split-Structure Characteristics

open access: yesAerospace
This study investigates the structural response of engine outer casings subjected to external pressure, with particular emphasis on the buckling resistance and sealing integrity of split-structure configurations.
Youzhi Xiang   +5 more
doaj   +1 more source

Influence of the external pressure on the quantum correlations of molecular magnets

open access: yes, 2016
The study of quantum correlations in solid state systems is a large avenue for research and their detection and manipulation are an actual challenge to overcome.
Alves, Á. S.   +6 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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