Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
THE FEATURES OF THE CRYSTALLIZATION PROCESS IN BIMETALLIC NANOSTRUCTURES UNDER EXTERNAL PRESSURE
In this paper the process of the structure formation in the bimetallic nanosystem Au – Ag of the equiatomic type at different external pressures has been investigated.
S.S. Bogdanov +6 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Nonlinear stability of thin FGM annular spherical segment in thermal environment
The nonlinear stability of functionally graded material (FGM) annular spherical segment resting on elastic foundations in thermal environment is studied analytically.
Vu Thi Thuy Anh +2 more
doaj +1 more source
Low-cost fabrication of high-performance composite structures using external compaction pressure
In the composite industry, wet lay-up and vacuum bagging are widely used, low-cost manufacturing processes. This paper investigates the mechanical performance of wet layup and vacuum bagged carbon fibre-reinforced laminates compressed in a hydraulic ...
Hall, Wayne +5 more
core +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
PEMBUKTIAN FRAUD TRIANGLE THEORY PADA FINANCIAL REPORT QUALITY
A perfect and qualified financial statements are the financial statements that each company wants to present. In this competitive era, presenting a good quality reports is a difficult thing for companies, so the thought arises to commit fraudulent ...
Edi Edi, Elis Victoria
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Long subcutaneous tunnelling reduces infection rates in paediatric external ventricular drains [PDF]
Purpose The aim of this study is to report the efficacy of long subcutaneous tunnelling of external ventricular drains in reducing rates of infection and catheter displacement in a paediatric population. Methods In children requiring external ventricular
Chakraborty, A +3 more
core
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source

