Results 61 to 70 of about 2,622,370 (297)

Evolutionary game of coalition building under external pressure [PDF]

open access: yes, 2017
We study the fragmentation-coagulation (or merging and splitting) evolutionary control model as introduced recently by one of the authors, where $N$ small players can form coalitions to resist to the pressure exerted by the principal.
A Saichev   +16 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Vented piston seal prevents fluid leakage between two chambers [PDF]

open access: yes, 1964
To prevent fluid leakage around piston seals separating two fluids under differential pressure, a venting system has been devised. Two methods may be used for venting seals through internal passages to an external low-pressure area, O-ring or split-ring ...
Mac Glashan, W. F., Morrison, R.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Acute Responses to Forearm Compression of Blood Lactate Accumulation, Heart Rate, Perceived Exertion, and Muscle Pain in Elite Climbers

open access: yesFrontiers in Physiology, 2018
Objectives: To evaluate the immediate responses to forearm compression of blood lactate concentration, heart rate, perceived exertion and local forearm muscle pain during severe climbing in elite climbers.Method: Seven elite climbers (18 ± 2 years; 164 ±
Florian Azad Engel   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

THE FEATURES OF THE CRYSTALLIZATION PROCESS IN BIMETALLIC NANOSTRUCTURES UNDER EXTERNAL PRESSURE

open access: yesФизико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2019
In this paper the process of the structure formation in the bimetallic nanosystem Au – Ag of the equiatomic type at different external pressures has been investigated.
S.S. Bogdanov   +6 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Nonlinear stability of thin FGM annular spherical segment in thermal environment

open access: yesVietnam Journal of Mechanics, 2015
The nonlinear stability of functionally graded material (FGM) annular spherical segment resting on elastic foundations in thermal environment is studied analytically.
Vu Thi Thuy Anh   +2 more
doaj   +1 more source

Pressure dependence of Raman modes in double wall carbon nanotubes filled with α-Fe. [PDF]

open access: yes, 2008
The preparation of highly anisotropic one-dimensional (1D) structures confined into carbon nanotubes (CNTs) in general is a key objective in CNTs research. In this work, the capillary effect was used to fill double wall carbon nanotubes with iron.
Borowiak-Palen E.   +20 more
core   +2 more sources

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