Results 121 to 130 of about 1,081,649 (264)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

External Quality Assessment of Molecular Testing for <i>HLA-B*58:01</i> Allele in Shanghai. [PDF]

Diagnostics (Basel)
Quan J, Zhang P, Xiao Y, Hu X, Bao Y.
europepmc   +1 more source

External Quality Assurance—A Personal View [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1999
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

External Quality Assessment as a strategy for Chagas disease surveillance: a study in four municipalities of Pernambuco. [PDF]

Rev Soc Bras Med Trop
Soares ENL, Rocha DDS, Seabra AP, Oliveira-Correia JPS, Moraes FVG, Silva RAE, Galvão C.   +6 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Precommercial thinning in naturally regenerated Scots pine stands in northern Finland

Silva Fennica, 1997
Tommi Ruha, Martti Varmola
doaj   +1 more source

Using native human sera to assess the suitability of external quality assessment materials based on testosterone, progesterone, and 17β-estradiol measurements. [PDF]

Front Mol Biosci
Vierbaum L, Kaiser P, Keller T, Weber S, Schellenberg I, Luppa PB, Wenzel F, Thevis M.   +7 more
europepmc   +1 more source

A model of external quality control

, 2015
The evaluation of histochemical techniques is qualitative and requires the use of positive controls, specific to each method. As this evaluation can be subjective, there is a great need for laboratories to participate, systematically, in external quality control schemes in histochemistry. In Portugal there is no such systematic control.
Frutuoso, José, Silva, Regina
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source