Results 131 to 140 of about 1,081,649 (264)

External quality assessment for yaws elimination in low- and middle-income countries using plasmid-based proficiency test items. [PDF]

PLoS Negl Trop Dis
Mueller C, Tchatchouang S, Basing LA, Ngazoa-Kakou S, Hugues KA, Handley BL, Beiras CG, Amanor IB, Ndzomo P, Bakheit MA, Becherer L, Tabah EN, Crucitti T, Borst N, Ries C, Lueert S, Frischmann S, Gmoser H, Landmann E, Sylla A, Kouamé-Sina SM, Arhinful D, Awondo P, Burl S, Harding-Esch EM, Tano A, Mitjà O, Eyangoh S, Addo KK, Marks M, Knauf S.   +30 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Piloting an Interpretive External Quality Assurance Model for Genomic Testing for Childhood Syndromes and Intellectual Disability. [PDF]

J Mol Diagn
Lundie B, Chai SY, Byrne AB, Azmanov D, Christodoulou J, Haas MA, Kassahn KS, Lunke S, Stott A, Thompson BA, Badrick T, Bennetts B.   +11 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Correction: Establishing an external quality assurance scheme for the detection of Orientia tsutsugamushi IgM in clinical samples: Strengthening quality control of scrub typhus diagnosis in Indian laboratories. [PDF]

PLoS Negl Trop Dis
Ratchagadasse VR, Vasudevan D, Philomenadin FS, Sivakumar H, Devanathan N, Kaur H, Mukhopadhyay L, Dhodapkar R.   +7 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Towards harmonization of Lyme diagnostics interpretation: external quality assessment using a web-based survey. [PDF]

Eur J Clin Microbiol Infect Dis
Hoeve-Bakker BJA, Kerkhof K, van Dam AP, Hovius JW, Voordouw ACG, Ter Hofstede H, Brandenburg AH, Thijsen SFT, Notermans DW.   +8 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Establishing an external quality assurance scheme for the detection of Orientia tsutsugamushi IgM in clinical samples: Strengthening quality control of scrub typhus diagnosis in Indian laboratories. [PDF]

PLoS Negl Trop Dis
Ratchagadasse VR, Vasudevan D, Philomenadin FS, Sivakumar H, Devanathan N, Kaur H, Mukhopadhyay L, Dhodapkar R.   +7 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source