Results 51 to 60 of about 2,984 (162)

The Italian External Quality Assessment (EQA) program on urinary sediment by microscopy examination: a 20 years journey

Clinical Chemistry and Laboratory Medicine (CCLM), 2020
Abstract Objectives In spite of the introduction of automated systems for urinary sediment analysis, microscopy examination remains the gold standard, and it is more than ever important to perform it with a good and reliable quality.
Secchiero S., Fogazzi G. B., Manoni F., Epifani M., Plebani M.   +4 more
openaire   +2 more sources

100 Years of von Willebrand Disease (VWD): Comparison of Historical and Contemporary von Willebrand Factor (VWF) Activity Assays in the Laboratory Identification of VWD

Haemophilia, EarlyView.
Abstract Introduction von Willebrand disease (VWD) is a prevalent bleeding disorder resulting from deficiencies and/or defects in von Willebrand factor (VWF). Accurately diagnosing VWD, particularly distinguishing between qualitative defects (types 2A, 2B, 2 M, and 2N) and quantitative defects (types 1 and 3), poses challenges that have significant ...
Emmanuel J. Favaloro, Sandya Arunachalam, Mahzuza Salwa, Ronny Vong, Leonardo Pasalic   +4 more
wiley   +1 more source

Beyond proficiency testing: Leveraging commutable External Quality Assessment data to harmonize tumor markers and refine medical decision points

Tumor Biology
Background Serum tumor markers such as carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), and prostate-specific antigen (PSA) are crucial to clinical decision-making based on defined medical thresholds. However, significant inter-method variability
Jong Do Seo, Huub H. Van Rossum, Yeo-Min Yun   +2 more
doaj   +1 more source

Comparability of thyroid-stimulating hormone immunoassays using fresh frozen human sera and external quality assessment data.

PLoS ONE, 2021
BackgroundThis study aimed to assess the comparability among assays using freshly frozen human sera and external quality assessment (EQA) data in China.MethodsTwenty-nine serum samples and two commercial EQA materials, obtained from the National Center ...
Shunli Zhang, Fei Cheng, Hua Wang, Jiangping Wen, Jie Zeng, Chuanbao Zhang, Wensong Liu, Ning Wang, Tingting Jia, Mo Wang, Rui Zhang, Yuhong Yue, Jing Xu, Zhanyong Wang, Yilong Li, Wenxiang Chen, Qingtao Wang   +16 more
doaj   +1 more source

UK recommendations for Ki‐67 immunohistochemical staining and interpretation in breast cancer

Histopathology, EarlyView.
Where possible, a validated digital imaging system should be utilized. If this is not available, then intermediate scores (5%–30%) should be thoroughly assessed using the Ki‐67 International Working Group guidance. Difficult cases should be double scored.
Abeer M Shaaban, Andrew Dodson, Emad Rakha, Ian Ellis, Daniel Rea, Cecily Quinn, Elena Provenzano, Sarah Pinder, on behalf of the UK National Coordinating Committee for Breast Pathology (NCCBP), Association of Breast Pathology (ABP) and the UK National External Quality Assessment Scheme for Immunohistochemistry and In Situ Hybridisation (UK NEQAS ICC & ISH)   +9 more
wiley   +1 more source

Quality control of malaria microscopy reveals misdiagnosed non-falciparum species and other microscopically detectable pathogens in Senegal

Annals of Clinical Microbiology and Antimicrobials, 2018
Background In developing countries, malaria diagnosis relies on microscopy and rapid diagnostic tests. In Senegal, national malaria control program (NMCP) regularly conducts supervisory visits in health services where malaria microscopy is performed.
Mamadou Alpha Diallo, Khadim Diongue, Mame Cheikh Seck, Mouhamadou Ndiaye, Ibrahima Diallo, Younouss Diedhiou, Tolla Ndiaye, Yaye Die Ndiaye, Aida Sadikh Badiane, Daouda Ndiaye   +9 more
doaj   +1 more source

Performance Assessment of Staclot‐LA Assay on Fully Automated Coagulation Analyser for Lupus Anticoagulant Testing Using Internal and External Quality Controls

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction It is recommended to detect lupus anticoagulant (LA) using two phospholipid‐dependent clotting assays, including a LA‐sensitive activated partial‐thromboplastin‐time (aPTT). Among these reagents, Staclot‐LA assay is performed on a mixture of test and normal plasma with and without hexagonal phase phospholipids.
V. Siguret, G. Jourdi, S. Melicine, L. Goubeau, Q. Pomorski, B. Joly‐Laffargue, A. Stepanian, M. Delrue, C. Bon, P. Meijer, E. Curis   +10 more
wiley   +1 more source

Results of a worldwide external quality assessment of cfDNA testing in lung Cancer

BMC Cancer, 2022
Background Circulating cell free DNA (cfDNA) testing of plasma for EGFR somatic variants in lung cancer patients is being widely implemented and with any new service, external quality assessment (EQA) is required to ensure patient safety.
Jennifer A. Fairley, Melanie H. Cheetham, Simon J. Patton, Etienne Rouleau, Marc Denis, Elisabeth M. C. Dequeker, Ed Schuuring, Kaat van Casteren, Francesca Fenizia, Nicola Normanno, Zandra C. Deans   +10 more
doaj   +1 more source

Different Analytical Modes on Automatic Hematology Analyzers for Testing Quality Control Materials and Commutability Assessment

International Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1365-1376, December 2026.
ABSTRACT Introduction Hematological disorders, critical for diagnosis, and monitoring, rely on accurate complete blood count results from automated analyzers, the reliability of which depends on robust quality control (QC). However, the ability of commutability of commercial hematology QC materials (HQCM) to behave like patient samples across different
Bingshuang Ren, Ya Cheng, Hongping Ba, Weijia Cheng, Xuwei Zhou, Hui Zhen, Shimin Wu, Jie Gong   +7 more
wiley   +1 more source

Testing for Non‐Severe Heritable Platelet Function Disorders

International Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1279-1288, December 2026.
ABSTRACT Heritable platelet function disorders (HPFD) are a diverse group of bleeding disorders characterised by a primary qualitative defect in platelet function rather than platelet number. HPFD may be broadly categorised according to the severity of bleeding, with Glanzmann thrombasthenia and Bernard Soulier syndrome classically considered severe ...
Kate Burley, Naomi Cornish, Maria Molina Carretero, Sarah K. Westbury   +3 more
wiley   +1 more source