Results 51 to 60 of about 137,198 (259)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Characterisation of the Wind Convection Losses in Plain and Ribbed Tubes of Solar Central Receivers via Tube-Resolved CFD Simulations

open access: yesSolarPACES Conference Proceedings
Convective losses due to wind affect the thermal efficiency of external central receivers of solar power towers (SPT), but their full characterization is still an unresolved question.
Jose Martín-Martínez   +3 more
doaj   +1 more source

The short-term effects of antenna insulation thickness on path losses in wireless telemetry implants at microwave frequencies

open access: yesEuropean Journal of Translational Myology, 2013
Various physiological parameters can be monitored non-invasively using wireless biotelemetry links. The development of sophisticated ultra low power consuming transceivers allows the transmission of large amounts of data from the inside of the body to an
Lukas Kneisz   +5 more
doaj   +1 more source

Heliostat aiming point optimization for external tower receiver

open access: yesSolar Energy, 2017
Abstract Reduction of peak fluxes on solar receiver is an important research topic because peak minimization can lead to lower receiver temperatures with advantages in terms of thermal efficiency and mechanical stresses. This work proposes different approaches for the minimization of the heat flux on external tower receiver with surround field.
Astolfi, Marco   +4 more
openaire   +1 more source

Performance assessment of a secondary concentrator for solar tower external receivers [PDF]

open access: yesAIP Conference Proceedings, 2019
In the EU-project RAISELIFE, a secondary concentrator for Solar Tower systems has been developed conceptually, which is discussed techno-economically herein. Based on a detailed three-level simulation methodology (optical assessment of radiation distribution on receiver surfaces, thermal FEM-simulation of receiver efficiency and transient system ...
Schöttl, Peter   +5 more
openaire   +3 more sources

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Custom-Designed Electrically Small Huygens Dipole Antennas Achieve Efficient, Directive Emissions Into Air When Mounted on a High Permittivity Block

open access: yesIEEE Access, 2019
System-on-Chip (SoC) applications include embedded systems and mobile computing platforms. They will play major roles in fifth generation (5G) wireless systems, notably with the many associated IoT (internet-of-things) devices.
Richard W. Ziolkowski
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Home - About - Disclaimer - Privacy