Results 101 to 110 of about 11,026 (316)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Metalinguistic Value Disagreement

open access: yesStudia Semiotyczne, 2019
DOI: http://doi.org/10.26333/sts.xxxi2.07 In a series of publications Burgess, Plunkett and Sundell have developed a metalinguistic negotiation view that they call ‘Conceptual Ethics.’ I argue that their position adequately captures our intuition that
Erich Rast
doaj  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

The Nyāya Argument for Disjunctivism [PDF]

open access: yes, 2019
The Nyāya school of classical Indian epistemology defended (by today’s standards) a radical version of epistemic externalism. They also gave arguments from their epistemological positions to an early version of disjunctivism about perceptual ...
Schiller, Henry Ian
core  

‘Quine’s Meaning Nihilism: Revisiting Naturalism and Confirmation Method,’ [PDF]

open access: yes, 2017
The paper concentrates on an appreciation of W.V. Quine’s thought on meaning and how it escalates beyond the meaning holism and confirmation holism, thereby paving the way for a ‘meaning nihilism’ and ‘confirmation rejectionism’.
Chakraborty, Dr Sanjit
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Intentional Identity and Coordination

open access: yesStudia Semiotyczne, 2019
DOI: http://doi.org/10.26333/sts.xxxi2.03 The concept of intentional identity has aroused considerable interests since Geach (1967). I argue, however, that the real import of intentional identity is still not duly appreciated. Drawing on three sets of
Hsiang-Yun Chen
doaj  

Premise Acceptability, Deontology, Internalism, Justification

open access: yesInformal Logic, 1995
Acceptability is a thoroughly normative epistemic notion. If a statement is acceptable, i.e. it is proper to take it as a premise, then one is justified in accepting it.
James B. Freeman
doaj   +1 more source

Unconscious Perception and Perceptual Knowledge [PDF]

open access: yes, 2017
It has been objected recently that naïve realism is inconsistent with an empirically well-supported hypothesis that unconscious perception is possible.
Zięba, Paweł J.
core  

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