Results 81 to 90 of about 4,293 (244)
Les gestes dans l’environnement numérique : la ponctuation des affects
Revue Française des Sciences de l’Information et de la Communication, 2017 Through the prism of an anthropological approach inspired by the externalist Theory, I propose to study the way digital tools have an impact on the morphology and rhythms of affects.
Peppe Cavallari
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2003 Introduction to externalism in the philosophy of mind and cognitive ...
Wilson, Robert A.
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Ceaseless, Unpredictable Creativity: Language as Technology
Biolinguistics, 2009 Notions like ‘biolinguistics’ have a trivial and a non-trivial interpretation. According to the trivial version, a cultural phenomenon like language is only based on our innate biological capacities. Language, in this view, is not a matter of biology per
Jan Koster
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Investigating the Fundamental Base of Emotion Science
PassionHow should we investigate folk emotion concepts for the purposes of anchoring scientific emotion concepts? In this article, I expand on Mun’s ideas on what she calls the fundamental base for interdisciplinary inquiry in the science of emotion.
Juan R. Loaiza
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Indexicality and semantic externalism
, 2023 Kripke (1972) notoriously claimed that, unlike descriptive terms whose defining features (intension) can be satisfied by different objects (have different extensions) in different worlds, proper names are rigid designators because their reference is ...
Leclercq, Bruno, De Brabanter, Philippe
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source