Results 101 to 110 of about 11,159 (315)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Lessons and new directions for extended cognition from social and personality psychology [PDF]
, 2017 This paper aims to expand the range of empirical work relevant to the extended cognition debates. First, I trace the historical development of the person-situation debate in social and personality psychology and the extended
Skorburg, Joshua August
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
EXTERNALISM, RELATIONAL SELVES, AND REDEMPTIVE RELATIONSHIPS
Zygon, 2011 . The dangerous level of individuality in contemporary Western culture is informed by a conception of mind, self, and soul as internal to the central nervous system.
doaj +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Externalist argument against medical assistance in dying for psychiatric illness. [PDF]
J Med Ethics, 2023 Maung HH.
europepmc +1 more source
Epistemology and Ontology of the Quality. An Introduction to the Enactive Approach to Qualitative Ontology [PDF]
, 2016 The concept of quality points at a significant philosophical problem. The issue of the ontological status of the qualities of experience and reality leads us to discuss the issues of naturalism and reductionism in philosophy of mind.
Pace Giannotta, Andrea
core +1 more source
Hierarchy Theory of Evolution and the Extended Evolutionary Synthesis: Some Epistemic Bridges, Some Conceptual Rifts [PDF]
, 2018 Contemporary evolutionary biology comprises a plural landscape of multiple co-existent conceptual frameworks and strenuous voices that disagree on the nature and scope of evolutionary theory.
A Etxeberria +113 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source