Results 71 to 80 of about 502 (266)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Les gestes dans l’environnement numérique : la ponctuation des affects
Revue Française des Sciences de l’Information et de la Communication, 2017 Through the prism of an anthropological approach inspired by the externalist Theory, I propose to study the way digital tools have an impact on the morphology and rhythms of affects.
Peppe Cavallari
doaj +1 more source
Externalist argument against medical assistance in dying for psychiatric illness. [PDF]
J Med Ethics, 2023 Maung HH.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Ceaseless, Unpredictable Creativity: Language as Technology
Biolinguistics, 2009 Notions like ‘biolinguistics’ have a trivial and a non-trivial interpretation. According to the trivial version, a cultural phenomenon like language is only based on our innate biological capacities. Language, in this view, is not a matter of biology per
Jan Koster
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Investigating the Fundamental Base of Emotion Science
PassionHow should we investigate folk emotion concepts for the purposes of anchoring scientific emotion concepts? In this article, I expand on Mun’s ideas on what she calls the fundamental base for interdisciplinary inquiry in the science of emotion.
Juan R. Loaiza
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Dretske's Naturalistic Representationalism and Privileged Accessibility Thesis. [PDF]
Philosophia (Ramat Gan), 2022 Sahu MK.
europepmc +1 more source