Results 51 to 60 of about 4,293 (244)

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak   +9 more
wiley   +1 more source

Spread Mind and Causal Theories of Content [PDF]

open access: yesAvant, 2014
In this paper, I analyze a type of externalist enactivism defended by Riccardo Manzotti. Such radical versions of enactivism are gaining more attention, especially in cognitive science and cognitive robotics.
Krystyna Bielecka
doaj  

Le menti non sono documenti (e viceversa)

open access: yesRivista Internazionale di Filosofia e Psicologia, 2021
In the theory of documentality, social objects are understood as inscribed acts; in extended mind theory, minds are considered to extend beyond the body to external processes and devices.
Giovanni Tuzet, Andrea Lavazza
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Algunos supuestos problemáticos del externismo estrictamente natural

open access: yesBajo Palabra, 2016
Pretendemos argumentar contra una cierta versión del externismo psicológico: el externismo estrictamente natural. Esta teoría se basa en una concepción cuestionable del significado de los términos de género natural, razón por la cual en el mejor de los ...
S. Andrés
doaj  

Is De Dicto motivation manifestly a no-go?

open access: yesRivista Internazionale di Filosofia e Psicologia
The aim of this paper is to challenge Michael Smith’s influential “fetishism charge” against motivational externalism – the view that moral judgments motivate only in the presence of a distinct conative state.
Irene Bosco
doaj   +1 more source

Revenge

open access: yesCrítica, 2018
This paper discusses, in a preliminary manner, what revenge is. (It does not address the rationality or moral standing of revenge.) In particular, it proposes four elements of revenge —an agent, a recipient, a harm intended by the former, and a harm ...
Robert J. Stainton
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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