Results 121 to 130 of about 11,026 (316)

What to believe about your belief that you're in the good case [PDF]

open access: yes, 2019
Going about our daily lives in an orderly manner requires us, once we are aware of them, to dismiss many metaphysical possibilities. We take it for granted that we are not brains in vats, or living in the Matrix, or in an extended dream.
Worsnip, Alex
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Scratching the structure of moral agency: insights from philosophy applied to neuroscience. [PDF]

open access: yesFront Neurosci, 2023
Castro-Toledo FJ   +2 more
europepmc   +1 more source

Epistemology and Ontology of the Quality. An Introduction to the Enactive Approach to Qualitative Ontology [PDF]

open access: yes, 2016
The concept of quality points at a significant philosophical problem. The issue of the ontological status of the qualities of experience and reality leads us to discuss the issues of naturalism and reductionism in philosophy of mind.
Pace Giannotta, Andrea
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EXTERNALISM, RELATIONAL SELVES, AND REDEMPTIVE RELATIONSHIPS

open access: yesZygon, 2011
.  The dangerous level of individuality in contemporary Western culture is informed by a conception of mind, self, and soul as internal to the central nervous system.
doaj   +2 more sources

How to Explain Miscomputation [PDF]

open access: yes, 2018
Just as theory of representation is deficient if it can’t explain how misrepresentation is possible, a theory of computation is deficient if it can’t explain how miscomputation is possible. Nonetheless, philosophers have generally ignored miscomputation.
Tucker, Chris
core  

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

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