Results 51 to 60 of about 263,768 (295)
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Ecology and Society, 2020 With the increasing number of adaptation plans being generated across the world at multiple scales and levels of organization, the issue of coordination among plans is emerging as a significant challenge.
Olivier Barreteau +6 more
doaj +1 more source
The correlation of externalities in marginal cost pricing: lessons learned from a real-world case study [PDF]
, 2016 Negative externalities cause inefficiencies in the allocation of capacities and resources in a transport system. Marginal social cost pricing allows to correct for these inefficiencies in a simulation environment and to derive real-world policy ...
Agarwal, Amit, Kickhöfer, Benjamin
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
IEEE AccessInterconnected power grids represent a significant advancement in sustainably and economically meeting global energy demands. However, a crucial gap persists in effectively integrating the costs of imported emissions into the power generation planning of
Shraf Eldin Sati +5 more
doaj +1 more source
Climate change and cancer: converging policies
Molecular Oncology, 2021 Intervening on risk factors for noncommunicable diseases (including cancer) in industrialized countries could achieve a reduction of between 30% and 40% of premature deaths.
Paolo Vineis +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Air pollution mortality from India’s coal power plants: unit-level estimates for targeted policy
Environmental Research LettersAir pollution from coal-fired electricity generation is an important cause of premature mortality in India. Although pollution-related mortality from the sector has been extensively studied, the relative contribution of individual coal-fired units to the
Kirat Singh +7 more
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source