Results 51 to 60 of about 266,760 (314)

Environmental and Economic Analysis of an Anaerobic Co-Digestion Power Plant Integrated with a Compost Plant

Energies, 2020
Italian power generation through anaerobic digestion (AD) has grown significantly between 2009 and 2016, becoming an important renewable energy resource for the country, also thanks to the generous incentives for produced electricity available in the ...
Sara Rajabi Hamedani, Mauro Villarini, Andrea Colantoni, Maurizio Carlini, Massimo Cecchini, Francesco Santoro, Antonio Pantaleo   +6 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Transfers of vulnerability through adaptation plan implementation: an analysis based on networks of feedback control loops

Ecology and Society, 2020
With the increasing number of adaptation plans being generated across the world at multiple scales and levels of organization, the issue of coordination among plans is emerging as a significant challenge.
Olivier Barreteau, John M. Anderies, Chloe Guerbois, Tara Quinn, Clara Therville, Raphael Mathevet, Francois Bousquet   +6 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Climate change and cancer: converging policies

Molecular Oncology, 2021
Intervening on risk factors for noncommunicable diseases (including cancer) in industrialized countries could achieve a reduction of between 30% and 40% of premature deaths.
Paolo Vineis, Inge Huybrechts, Christopher Millett, Elisabete Weiderpass   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A Methodological Approach With Application to Integrating Carbon Emission Externalities Costs in Unit Commitment

IEEE Access
Interconnected power grids represent a significant advancement in sustainably and economically meeting global energy demands. However, a crucial gap persists in effectively integrating the costs of imported emissions into the power generation planning of
Shraf Eldin Sati, Ahmed M. Abdelemam, Ammar Atif Abdalla, Wahab Ullah, Musaab Salih, Adolf Acquaye   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Air pollution mortality from India’s coal power plants: unit-level estimates for targeted policy

Environmental Research Letters
Air pollution from coal-fired electricity generation is an important cause of premature mortality in India. Although pollution-related mortality from the sector has been extensively studied, the relative contribution of individual coal-fired units to the
Kirat Singh, Tapas Peshin, Shayak Sengupta, Sumil K Thakrar, Christopher W Tessum, Jason D Hill, Inês M L Azevedo, Stephen P Luby   +7 more
doaj   +1 more source