Results 71 to 80 of about 342,951 (316)

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

open access: yesAdvanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi   +8 more
wiley   +1 more source

Re-evaluating the general dynamic theory of oceanic island biogeography

open access: yesFrontiers of Biogeography, 2013
The general dynamic model of oceanic island biogeography integrates temporal changes in ecological circumstances with diversification processes, and has stimulated current research in island biogeography.
Manuel Jonas Steinbauer   +4 more
doaj  

ERK1/2: A Key Cellular Component for the Formation, Retrieval, Reconsolidation and Persistence of Memory

open access: yesFrontiers in Molecular Neuroscience, 2018
Extracellular regulated kinase 1/2 (ERK1/2) has been strongly implicated in several cellular processes. In the brain ERK1/2 activity has been primarily involved in long-term memory (LTM) formation and expression.
Jorge H. Medina   +2 more
doaj   +1 more source

A Mobile Phone App for the Generation and Characterization of Motor Habits

open access: yesFrontiers in Psychology, 2020
Habits are a powerful route to efficiency; the ability to constantly shift between goal-directed and habitual strategies, as well as integrate them into behavioral output, is key to optimal performance in everyday life.
Paula Banca   +7 more
doaj   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

open access: yesAdvanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno   +16 more
wiley   +1 more source

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

open access: yesAdvanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno   +15 more
wiley   +1 more source

Stochastic two-species mutualism model with jumps

open access: yesModern Stochastics: Theory and Applications, 2020
The existence and uniqueness are proved for the global positive solution to the system of stochastic differential equations describing a two-species mutualism model disturbed by the white noise, the centered and non-centered Poisson noises.
Olga Borysenko, Oleksandr Borysenko
doaj   +1 more source

Estimation of glacier ice extinction using long-wavelength airborne Pol-InSAR

open access: yes, 2013
In recent years there has been increased interest in using synthetic aperture radar (SAR) to study and monitor glaciers and ice sheets for glaciological and climate change research.
Sharma, Jayanti   +3 more
core   +1 more source

Water Permeates and Plasticizes Amorphous Carbon Dots: Unraveling the Inner Accessibility of the Nanoparticles by Glass Transition Studies

open access: yesAdvanced Materials, EarlyView.
The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti   +8 more
wiley   +1 more source

Are AMPA Receptor Positive Allosteric Modulators Potential Pharmacotherapeutics for Addiction?

open access: yesPharmaceuticals, 2013
Positive allosteric modulators (PAMs) of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are a diverse class of compounds that increase fast excitatory transmission in the brain.
Lucas R. Watterson, M. Foster Olive
doaj   +1 more source

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