Tumor Metabolism in the Microenvironment of Nodal Metastasis in Head and Neck Squamous Cell Carcinoma [PDF]
, 2015 Introduction: Monocarboxylate transporter 4 (MCT4) is a cell membrane transporter of lactate. MCT4 is a tumor-specific marker of oxidative stress, glycolysis and hypoxia in tumor stromal cells.
Adam Luginbuhl +9 more
core +2 more sources
Adjuvant vs. salvage radiation therapy in men with high-risk features after radical prostatectomy: Survey of North American genitourinary expert radiation oncologists [PDF]
, 2019 INTRODUCTION: The management of patients with high-risk features after radical prostatectomy (RP) is controversial. Level 1 evidence demonstrates that adjuvant radiation therapy (RT) improves survival compared to no treatment; however, it may ...
Chen, Yiyi +4 more
core +1 more source
Advances in the management of HPV-related oropharyngeal cancer [PDF]
, 2019 Patients with human papillomavirus- (HPV-) related oropharyngeal squamous cell carcinoma (OPSCC) have a better prognosis than HPV-negative OPSCC when treated with standard high-dose cisplatin-based chemoradiotherapy.
Brugnoletti, O. +6 more
core +1 more source
Endothelin‐1: a predictor of extracapsular extension in clinically localized prostate cancer? [PDF]
BJU International, 2010 What’s known on the subject? and What does the study add? ET‐1 expression on initial prostate biopsies combined with PSA > 10 ng/ml and Gleason score ≥7 provided the best model for predicting extracapsular extension.
Johann, Menard +8 more
openaire +2 more sources
Serine-arginine protein kinase 1 (SRPK1), a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion [PDF]
, 2015 Vascular endothelial growth factor (VEGF) undergoes alternative splicing to produce both proangiogenic and antiangiogenic isoforms. Preferential splicing of proangiogenic VEGF is determined by serine-arginine protein kinase 1 (SRPK1), which is ...
Bullock, Nicholas +6 more
core +2 more sources
The Role of Multiparametric MRI in the Local Staging of Prostate Cancer
Frontiers in Bioscience-Elite, 2023 Prostate cancer ranks as the second most frequently diagnosed cancer globally among men and stands as the fifth leading cause of cancer-related death in males. Hence, an early and precise diagnosis and staging are critical.
Tiago Oliveira +5 more
doaj +1 more source
Prognostic value of the percentage of positive fragments in biopsies from patients with localized prostate cancer [PDF]
, 2005 OBJECTIVE: To assess the prognostic value of the percentage of positive fragments (PPF) in biopsies from patients with localized prostate cancer (PCa) undergoing radical prostatectomy.
Antunes, Alberto A. +5 more
core +3 more sources
Long term results of postoperative Intensity-Modulated Radiation Therapy (IMRT) in the treatment of Squamous Cell Carcinoma (SCC) located in the oropharynx or oral cavity [PDF]
, 2015 Background: To report our long-term results with postoperative intensity-modulated radiation therapy (IMRT) in patients suffering from squamous-cell carcinoma (SCC) of the oral cavity or oropharynx.
Debus, Jürgen +7 more
core +2 more sources
Urology Video Journal, 2019 Objectives: To report the feasibility of a console integrated augmented reality model during robotic assisted radical prostatectomy (AR-RARP) developed from combining the results of prostate multiparametric magnetic-resonance-imaging (mpMRI) and a ...
Stefano Puliatti +8 more
doaj +1 more source
Mischievous malakoplakia: A potential pitfall of mpMRI of the prostate?
Urology Case Reports, 2020 Interpretation of multiparametric magnetic resonance imaging (mpMRI) for prostate cancer diagnosis and staging can be challenging and, in some cases, benign prostate disease can mimic locally advanced malignancy. We present the case of a 57 year-old male
Michael E. Rezaee +4 more
doaj +1 more source