Results 191 to 200 of about 2,129,035 (302)

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

In situ detection of extracellular vesicles in breast cancer

Extracellular vesicles (EVs) are small vesicles secreted by a variety of cells into the extracellular space. The role of EVs in cancer biology is well established. It's been reported that EVs-mediated intercellular communication can promote cell growth
Pekovic-Vaughan, Vanja, Korać, Bato, Stojanović, Sara, Golić, Igor, Zakić, Tamara, Korać, Aleksandra, Čvoro, Aleksandra, Janković, Aleksandra   +7 more
core   +1 more source

Neutral Sphingomyelinase 2-Dependent Secretory Pathway May Contribute to Extracellular Hepatitis A Virus RNA Levels. [PDF]

Viruses
Sasaki-Tanaka R, Kanda T, Yamazaki H, Yamazaki S, Jimbo R, Yoshida T, Kimura N, Abe H, Yokoo T, Sakamaki A, Kamimura H, Kamimura K, Okamoto H, Terai S.   +13 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

<i>Erratum</i> to: "Extracellular vesicles mediate the communication between multiple myeloma and bone marrow microenvironment in a NOTCH dependent way". [PDF]

Haematologica
Giannandrea D, Platonova N, Colombo M, Mazzola M, Citro V, Adami R, Maltoni F, Ancona S, Dolo V, Giusti I, Basile A, Pistocchi A, Cantone L, Bollati V, Casati L, Calzavara E, Turrini M, Lesma E, Chiaramonte R.   +18 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Investigation of Matrix Metalloproteinase-Related Genetic Variations Associated With Cavity Formation in Pulmonary Tuberculosis. [PDF]

J Korean Med Sci
Zo S, Choi H, Kim SH, Yoon YE, Yun JW, Lee H.   +5 more
europepmc   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source