Results 1 to 10 of about 3,321,426 (398)

Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer

open access: yesCell, 2022
Tumor-resident intracellular microbiota is an emerging tumor component that has been documented for a variety of cancer types with unclear biological functions. Here, we explored the functional significance of these intratumor bacteria, primarily using a
Aikun Fu, Tingting Dong, Shang Cai
exaly   +2 more sources

Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts

open access: yesChemical Reviews, 2018
Intracellular delivery is a key step in biological research and has enabled decades of biomedical discoveries. It is also becoming increasingly important in industrial and medical applications ranging from biomanufacture to cell-based therapies. Here, we
Martin Philip Stewart   +2 more
exaly   +2 more sources

The exosome journey: from biogenesis to uptake and intracellular signalling

open access: yesCell communication and signaling : CCS, 2021
The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials testing exosomes for diagnostic and therapeutic applications are generating remarkable interest from the scientific community and investors.
Sonam Gurung   +3 more
semanticscholar   +1 more source

Effect of topical use of solution containing ferrous ions on treatment efficacy in women with recurrent urogenital trichomoniasis [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2022
Objective. To assess effect of topical use of solution containing ferrous ions on efficacy of metronidazole therapy in women with recurrent urogenital trichomoniasis. Materials and Methods.
Cherkasova Yu.I.   +3 more
doaj   +1 more source

Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors

open access: yesScience, 2023
Decreased dendritic spine density in the cortex is a hallmark of several neuropsychiatric diseases, and the ability to promote cortical neuron growth has been hypothesized to underlie the rapid and sustained therapeutic effects of psychedelics ...
Maxemiliano V. Vargas   +13 more
semanticscholar   +1 more source

Complosome — the intracellular complement system

open access: yesNature Reviews Nephrology, 2023
The complement system is a recognized pillar of host defence against infection and noxious self-derived antigens. Complement is traditionally known as a serum-effective system, whereby the liver expresses and secretes most complement components, which ...
E. West, C. Kemper
semanticscholar   +1 more source

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

open access: yesScience, 2020
Profiling tumor bacteria Bacteria are well-known residents in human tumors, but whether their presence is advantageous to the tumors or to the bacteria themselves has been unclear.
D. Nejman   +60 more
semanticscholar   +1 more source

Multifunctional intracellular matrix metalloproteinases: implications in disease

open access: yesThe FEBS Journal, 2021
Matrix metalloproteinases (MMPs) are zinc‐dependent endopeptidases that were first discovered as proteases, which target and cleave extracellular proteins. During the past 20 years, however, intracellular roles of MMPs were uncovered and research on this
Wesam Bassiouni, M. Ali, R. Schulz
semanticscholar   +1 more source

Selective autophagy of intracellular organelles: recent research advances

open access: yesTheranostics, 2021
Macroautophagy (hereafter called autophagy) is a highly conserved physiological process that degrades over-abundant or damaged organelles, large protein aggregates and invading pathogens via the lysosomal system (the vacuole in plants and yeast ...
Wen Li   +25 more
semanticscholar   +1 more source

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