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Physical Principles Underlying the Complex Biology of Intracellular Phase Transitions.

open access: yesAnnual Review of Biophysics, 2020
Many biomolecular condensates appear to form via spontaneous or driven processes that have the hallmarks of intracellular phase transitions. This suggests that a common underlying physical framework might govern the formation of functionally and ...
Jeong-Mo Choi, A. Holehouse, R. Pappu
semanticscholar   +1 more source

Intracellular trafficking [PDF]

open access: yesWormBook, 2006
Studies in C. elegans have begun to reveal new components and new mechanisms associated with intracellular membrane traffic in a variety of cell types. The worm benefits from many of the advantages of yeast as a genetically tractable organism for these kinds of studies while offering the unique opportunity to probe how these pathways have been extended
Barth D, Grant, Miyuki, Sato
openaire   +2 more sources

GUT MICROSYMBIOCENOSIS IN CHILDREN WITH REACTIVE ARTHRITIS

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. To study the state of gut microsymbiocenosis in children with reactive arthritis (RA), with the assessment of biofilm formation (BFF) of microsymbionts and the ability to change cytokine levels (their anticytokine activity) in vitro.
O. V. Bukharin   +9 more
doaj   +1 more source

Intracellular mechanisms underlying the nicotinic enhancement of LTP in the rat dentate gyrus [PDF]

open access: yes, 2008
We have previously shown that activation of nicotinic acetylcholine receptors (nAChRs) enhanced long-term potentiation (LTP) in the rat dentate gyrus in vitro via activation of α7 nAChR. In the present studies, mechanisms underlying the acute and chronic
Abel   +81 more
core   +1 more source

GENETIC CHARACTERISTICS OF THE ADAPTIVE POTENTIAL OF BIFIDOBACTERIA IN THE BIOTOPE OF DISTAL HUMAN INTESTINE

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. Determination of distinctive parameters of the B. bifidum and B. longum genomes, which characterizes their adaptive potential applied to distal intestine biotope of the human gut. Materials and methods. 5 strains of bifidobacteria have been used: B.
S. V. Andryuschenko   +4 more
doaj   +1 more source

METABOLIC PROFILE OF BIFIDOFLORA UNDER DIFFERENT MICROECO-LOGICAL CONDITIONS OF THE COLON BIOTOPE IN HUMAN

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. To study the spectrum and level of short-chained fatty acids (SCFA) in supernatant of bifidobacteria under different microecological conditions of the colon biotope in human. Materials and methods.
O. V. Bukharin   +4 more
doaj   +1 more source

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.

open access: yesNeuron, 2003
The neuropathological correlates of Alzheimer's disease (AD) include amyloid-beta (Abeta) plaques and neurofibrillary tangles. To study the interaction between Abeta and tau and their effect on synaptic function, we derived a triple-transgenic model ...
S. Oddo   +9 more
semanticscholar   +1 more source

INTERMICROBIAL «SELF-NON-SELF» DISCRIMINATION IN «DOMINANT-ASSO-CIANT» PAIR OF PROBIOTIC STRAINS OF ESCHERICHIA COLI M-17 AND E.COLI LEGM-18

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. To use earlier developed method of intermicrobial «self-non-self» discrimination in «dominant-associant» pair for the assessment of foreignness of probiotic cultures of Escherichia coli M-17 (with pathogenicity island) and E.
O. V. Bukharin   +3 more
doaj   +1 more source

FUNCTIONAL GROUPS OF BIFIDOFLORA OF INTESTINAL MICROBIOTA IN ASSOCIATIVE SYMBIOSIS OF HUMAN

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. Aim of the research is the identification of functional groups of human gut bifidoflora based on analysis of the spectrum of metabolites features, proteome, bioprofile, immunoregulatory properties and the ability to differentiate «self/non-self ...
O. V. Bukharin   +3 more
doaj   +1 more source

In vitro effects of intestinal microsymbionts on the cytokine production

open access: yesМедицинская иммунология, 2023
The most important role in homeostasis of intestinal immune belongs to the immunoregulatory properties of the microbiota which activates intracellular signaling systems, cytokine expression, production of protective factors and limits inflammatory ...
O. V. Bukharin   +7 more
doaj   +1 more source

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