Results 31 to 40 of about 1,812,771 (319)

Mouse Syngeneic Melanoma Model with Human Epidermal Growth Factor Receptor Expression

Pharmaceutics, 2022
The development of epidermal growth factor receptor (EGFR)-targeting agents for the treatment of malignant melanoma requires cheap and easy animal tumor models for high-throughput in vivo screening.
Tatiana A. Slastnikova, Andrey A. Rosenkranz, Alexey V. Ulasov, Yuri V. Khramtsov, Tatiana N. Lupanova, Georgii P. Georgiev, Alexander S. Sobolev   +6 more
doaj   +1 more source

Pharmacological Characterization of a Recombinant Mitochondrial ROMK2 Potassium Channel Expressed in Bacteria and Reconstituted in Planar Lipid Bilayers

Membranes, 2023
In the inner mitochondrial membrane, several potassium channels that play a role in cell life and death have been identified. One of these channels is the ATP-regulated potassium channel (mitoKATP).
Milena Krajewska, Adam Szewczyk, Bogusz Kulawiak, Piotr Koprowski   +3 more
doaj   +1 more source

Gold nanoparticles explore cells: cellular uptake and their use as intracellular probes [PDF]

, 2014
Understanding uptake of nanomaterials by cells and their use for intracellular sensing is important for studying their interaction and toxicology as well as for obtaining new biological insight.
Septiadi, Dedy, Barker, Roger A., Huefner, Anna, Fragniere, Alexandra, Mahajan, Sumeet, Kuan, Wei-Li, Wilts, Bodo D., Patel, Imran I.   +7 more
core   +1 more source

Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells : role of sphingosine kinase 1 and S1P lyase [PDF]

, 2011
Earlier we have shown that extracellular sphingosine-1-phosphate (S1P) induces migration of human pulmonary artery endothelial cells (HPAECs) through the activation of S1P(1) receptor, PKCε, and PLD2-PKCζ-Rac1 signaling cascade.
Sabbadini Roger A., Satish Kalari, Nigel J. Pyne (356726), Garcia, Joe G N, Pyne Nigel J., Nigel J Pyne, Susan Pyne (356727), Natarajan Viswanathan, Pyne, S, Zhao, Y, Roger A. Sabbadini (7924547), Berdyshev, Evgeny V, Garcia, JGN, Roger A Sabbadini, Peter Usatyuk (356723), Garcia Joe G. N., Satish Kalari (307462), Nigel J. Pyne, Berdyshev Evgeny V., Natarajan, V, Usatyuk, Peter, Yutong Zhao, Kalari Satish, Garcia, Joe G.N., Usatyuk, P, Kalari, S, Sabbadini, RA, Viswanathan Natarajan, Roger A. Sabbadini, Joe G. N. Garcia (7923365), Evgeny V Berdyshev, Zhao Yutong, Joe G N Garcia, Sabbadini, Roger A, Pyne, Nigel J, Pyne, NJ, Pyne Susan, Yutong Zhao (356724), Evgeny V. Berdyshev (7924544), Irina Gorshkova (356721), Gorshkova, Irina, Usatyuk Peter, Kalari, Satish, Pyne, Susan, Irina Gorshkova, Gorshkova, I, Evgeny V. Berdyshev, Joe G. N. Garcia, Gorshkova Irina, Peter Usatyuk, Natarajan, Viswanathan, Berdyshev, EV, Susan Pyne, Zhao, Yutong, Viswanathan Natarajan (307479)   +54 more
core   +1 more source

Intracellular and extracellular tau [PDF]

Frontiers in Neuroscience, 2010
In this short review is described the toxicity of modified intracellular tau and that of extracellular tau that could be released into the extracellular space after neuron death.
Jesus Avila, Jesus Avila
openaire   +4 more sources

GENETIC PROFILE STAPHYLOCOCCUS AUREUS, ISOLATED FROM BACTERIAL CARRIERS AND PATIENTS WITH INFECTIOUS INFLAMMATORY PATHOLOGY

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. A comparative genetic evaluation of the pathogenic potential of Staphylococcus aureus strains isolated from bacterial carriers and patients with infectious inflammatory pathology. Materials and methods. The presence of pathogenicity genes (ssp, spa,
V. A. Gritsenko, A. R. Mavzyutov, T. M. Pashkova, O. L. Kartashova, Ya. V. Tyapaeva, Yu. P. Belozertseva   +5 more
doaj   +1 more source

The Obligate Intracellular Lifestyle [PDF]

Frontiers in Microbiology, 2011
Obligate intracellular bacteria represent consummate parasites, often covertly co-opting host resources to enable development and ultimately transmission to a new host. The overall success of this survival strategy is doubtless derived from co-evolution with respective eukaryotic hosts over hundreds of millions of years.
Fields, Kenneth A, Heinzen, Robert A, Carabeo, Rey   +2 more
openaire   +4 more sources

PHYSIOLOGICAL FEATURES OF CORYNEBACTERIA OF FEMALE REPRODUCTIVE TRACT

Журнал микробиологии, эпидемиологии и иммунобиологии, 2017
Literature data and results of authors’ research on biological properties of corynebacteria of reproductive tract of women are analyzed. General characteristics of microorganisms is given. 20 species of corynebacteria are presented: C.
L. V. Gladysheva, S. V. Cherkasov
doaj   +1 more source

Intracellular fate of bioresponsive poly(amidoamine)s in vitro and in vivo [PDF]

, 2010
Linear poly(amidoamine)s (PAAs) have been designed to exhibit minimal non-specific toxicity, display pH-dependent membrane lysis and deliver genes and toxins in vitro.
Nathalie Lavignac, R. Duncan, Richardson, Simon C.W., Duncan, Ruth, P. Ferruti, S. C. W. Richardson, N. Lavignac, N. G. Pattrick, Nicola G. Pattrick, Paolo Ferruti, Simon C.W. Richardson, Pattrick, Nicola G., Ferruti, Paolo, Lavignac, Nathalie, Richardson, Simon C. W., Ruth Duncan   +15 more
core   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source