Results 41 to 50 of about 1,812,771 (319)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Evidence of two differentially regulated elongasomes in Salmonella

Communications Biology, 2023
Cell shape is genetically inherited by all forms of life. Some unicellular microbes increase niche adaptation altering shape whereas most show invariant morphology.
Sónia Castanheira, Francisco García-del Portillo   +1 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Molecular Characterization of a Novel Intracellular ADP-Ribosyl Cyclase

, 2007
Background. ADP-ribosyl cyclases are remarkable enzymes capable of catalyzing multiple reactions including the synthesis of the novel and potent intracellular calcium mobilizing messengers, cyclic ADP-ribose and NAADP.
Jonathan S Marchant, Marchant, JS, Michael J Boulware, Dev Churamani, Churamani, D, Dale, L, Geach Timothy J., Martin Andrew C.R., Gary W Moy, Andrew C R Martin, Sandip Patel, Dale Leslie, Yi-Hsien Su, Vacquier, VD, Vacquier Victor D., Su, YH, Patel Sandip, Churamani Dev, Boulware, MJ, Marchant Jonathan S., Leslie Dale, Boulware Michael J., Moy Gary W., Patel, S, Geach, TJ, Su Yi-Hsien, Moy, GW, Timothy J Geach, Martin, ACR, Victor D Vacquier   +29 more
core   +1 more source

Establishing the intracellular niche of obligate intracellular vacuolar pathogens

Frontiers in Cellular and Infection Microbiology, 2023
Obligate intracellular pathogens occupy one of two niches – free in the host cell cytoplasm or confined in a membrane-bound vacuole. Pathogens occupying membrane-bound vacuoles are sequestered from the innate immune system and have an extra layer of protection from antimicrobial drugs. However, this lifestyle presents several challenges.
Tatiana M. Clemente, Rajendra K. Angara, Stacey D. Gilk   +2 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

DETECTION OF POTENTIALLY PATHOGENIC BACTERIA IN THE BRACKISH RIVERS FLOWING INTO THE ELTON LAKE BY HIGH-THROUGHPUT SEQUENCING

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. To indicate potentially pathogenic bacteria in plankton of the brackish rivers flowing into the Elton Lake by high-throughput sequencing of 16S ssuRNA gene. Materials and methods. The water samples from brackish rivers Lantsug and Chernavka, flowing
E. A. Selivanova, Yu. A. Khlopko, N. E. Gogoleva, A. O. Plotnikov   +3 more
doaj   +1 more source

Temperatures Outside the Optimal Range for Helicobacter pylori Increase Its Harboring within Candida Yeast Cells

Biology, 2021
Helicobacter pylori is capable of entering into yeast, but the factors driving this endosymbiosis remain unknown. This work aimed to determine if temperatures outside the optimal range for H. pylori increase its harboring within Candida. H.
Kimberly Sánchez-Alonzo, Luciano Arellano-Arriagada, Susana Castro-Seriche, Cristian Parra-Sepúlveda, Humberto Bernasconi, Héctor Benavidez-Hernández, Víctor L. Campos, Katia Sáez, Carlos T. Smith, Apolinaria García-Cancino   +9 more
doaj   +1 more source

Intracellular zinc modulates cardiac ryanodine receptor-mediated calcium release

, 2015
This work was supported by University of St. Andrews, Tenovus Scotland Grant T14/35 (to S. J. P.), British Heart Foundation Grant FS/14/69/31001 (to S. J.
Woodier, Jason, J. Woodier (7634894), S. J. Pitt (7634900), A. J. Stewart (7634897), Pitt, Samantha Jane, Stewart, Alan J., Rainbow, Richard D., Richard D. Rainbow (7619696)   +7 more
core   +1 more source

An intracellular pH gradient in the anammox bacterium Kuenenia stuttgartiensis as evaluated by (31)P NMR [PDF]

, 2009
The cytoplasm of anaerobic ammonium oxidizing (anammox) bacteria consists of three compartments separated by membranes. It has been suggested that a proton motive force may be generated over the membrane of the innermost compartment, the “anammoxosome ...
Van der Star, W.R.L. (author), Dijkema, C., Wouter R. L. van der Star, Pieter de Waard, van Loosdrecht, M., Strous, M. (author), van Loosdrecht, Mark C. M., van der Star, W., van der Star, Wouter R. L., Mark C. M. van Loosdrecht, Picioreanu, Cristian, Loosdrecht, M.C.M., van, Picioreanu, C. (author), Star, W.R.L., van der, De Waard, P. (author), Strous, Marc, de Waard, Pieter, Marc Strous, Van Loosdrecht, M.C.M., Dijkema, Cor, Dijkema, C. (author), Van der Star, W.R.L., Strous, M., Picioreanu, C., Cor Dijkema, Cristian Picioreanu, Van Loosdrecht, M.C.M. (author), Waard, P., de, De Waard, P.   +28 more
core   +1 more source