Results 61 to 70 of about 2,634,864 (332)

Real-Time Amperometric Recording of Extracellular H2O2 in the Brain of Immunocompromised Mice: An In Vitro, Ex Vivo and In Vivo Characterisation Study

open access: yesSensors, 2017
We detail an extensive characterisation study on a previously described dual amperometric H2O2 biosensor consisting of H2O2 detection (blank) and degradation (catalase) electrodes.
Caroline H. Reid, Niall J. Finnerty
doaj   +1 more source

OLIgo mass profiling (OLIMP) of extracellular polysaccharides. [PDF]

open access: yes, 2010
The direct contact of cells to the environment is mediated in many organisms by an extracellular matrix. One common aspect of extracellular matrices is that they contain complex sugar moieties in form of glycoproteins, proteoglycans, and/or ...
Gille, Sascha   +2 more
core   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Neutrophil extracellular traps [PDF]

open access: yesCurrent Biology, 2011
What are neutrophil extracellular traps, or NETs? Neutrophils, the most abundant immune cells in humans, are the first line of defense against invading pathogens. They employ a wide array of anti-microbial strategies, most notably phagocytosis, to attack and eliminate pathogens.
Amulic, Borko, Hayes, Garret
openaire   +4 more sources

Dosing extracellular vesicles

open access: yesAdvanced Drug Delivery Reviews, 2021
Extracellular vesicles (EVs) are natural nanoparticles containing biologically active molecules. They are important mediators of intercellular communication and can be exploited therapeutically by various bioengineering approaches. To accurately determine the therapeutic potential of EVs in pre-clinical and clinical settings, dependable dosing ...
Gupta, Dhanu   +2 more
openaire   +3 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

eDNA State and Medium Affect DNA Degradation Patterns in Seminatural Systems of Southern African Waterholes

open access: yesEnvironmental DNA
Environmental DNA (eDNA) has evolved into a valuable asset of the ecologists' toolkit, enabling time‐ and cost‐efficient biodiversity assessments in a wide variety of ecosystems.
Irmgard Sedlmayr, Tamara Schenekar
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Geometry based dynamic modeling of the neuron-electrode interface [PDF]

open access: yes, 2000
A dynamic model of the neuron-electrode interface is presented which is based on the interface geometry and the electrical properties of the neuronal membrane. The model is used to compute the potential at the electrode and the local membrane potentials.
Buitenweg, J.R.   +2 more
core   +3 more sources

The role of extracellular DNA in neutrophil extracellular traps [PDF]

open access: yes, 2013
Pseudomonas aeruginosa is an opportunistic pathogen and the primary pathogen in lung infections in patients with Cystic Fibrosis (CF). Neutrophils are recruited to the site of infection to clear the invading bacteria by phagocytosis and neutrophil extracellular trap (NET) formation.
openaire   +2 more sources

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