Results 121 to 130 of about 1,434,762 (289)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Bioactives and Extracellular Enzymes Obtained from Fermented Macrofungi Cultivated in Cotton and Jatropha Seed Cakes. [PDF]

open access: yesMicroorganisms, 2022
Cunha JRB   +9 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Abiotic and biotic factors in the nutrient solution and filter skin (Schmutzdecke) of slow filters integrated to closed hydroponic greenhouse systems [PDF]

open access: yes, 2006
Rapid pathogen dispersal by circulating nutrient solutions in closed hydroponic systems poses a major threat to this production method. Slow filtration is very effective against important fungal pathogens such as Phytophthora cryptogea and Pythium ...
Furtner, Bernhard
core   +1 more source

Ecomicrobiology and microbial assimilative capacity of the oligotrophic Andean Lake Laja, Chile Ecomicrobiología y capacidad asimilativa microbiana del lago oligotrófico andino Laja, Chile

open access: yesRevista Chilena de Historia Natural, 2011
A strong socio-economic development pressure in South Chile will more and more cause an impact to the present lakes and rivers. Nevertheless, our knowledge concerning the ecological structure and the microbial self-purification capabilities of these ...
BERNHARD KARRASCH   +6 more
doaj  

Long-Term Pepper (Capsicum annuum L.) Monoculture Reshapes Rhizosphere Soil Chemistry, Microbiota, and Metabolite Profiles

open access: yesAgriculture
Continuous monoculture alters rhizosphere soil conditions and microbial community structure, but the integrated soil biochemical, microbial, and metabolomic responses of pepper (Capsicum annuum L.) rhizosphere soils remain insufficiently characterized ...
Fan Yang   +8 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Nitrogen-Fixing Trees Shift Soil Organic Carbon Toward Mineral-Associated Stability by Enhancing Microbial-Derived Carbon in Subtropical Plantations

open access: yesPlants
Introducing nitrogen (N)-fixing trees into plantations is a promising strategy to increase soil organic carbon (SOC) storage. However, whether this practice enhances SOC stability, a key determinant of long-term carbon sequestration, and through which ...
Hongwei Bai   +6 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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