Results 111 to 120 of about 1,434,762 (289)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Characterization of pectin lyases on pectins and methyl oligogalacturonates [PDF]

, 1972
Pure saturated and unsaturated oligogalacturonic acids, including unsaturated monogalacturonic acid, were isolated and characterized. Their ultraviolet absorbance at 232 run, and their reactivities in the periodate thiobarbituric acid test and carbazole ...
Voragen, A.G.J.
core  

Extracellular enzymes secreted in the mycelial block of Lentinula edodes during hyphal growth. [PDF]

AMB Express, 2023
Kobayashi N, Wada N, Yokoyama H, Tanaka Y, Suzuki T, Habu N, Konno N.   +6 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Isolation and characterisation of two chymotrypsins from Allocyttus niger (black oreo dory) viscera [PDF]

, 1997
Two serine proteases from the viscera of deep-sea fish, black oreo dory (Allocyttus niger),were purified by hydrophobic, affinity, and cation exchange chromatography.
Krzyzosiak, J., Daniel, Roy M.
core  

Carbohydrate utilization and metabolism is highly differentiated in Agaricus bisporus [PDF]

, 2013
Background: Agaricus bisporus is commercially grown on compost, in which the available carbon sources consist mainly of plant-derived polysaccharides that are built out of various different constituent monosaccharides.
Eastwood, Daniel C., Patyshakuliyeva, Aleksandrina, Coutinho, Pedro M., de Vries, Ronald P., Gruben, B.S., Zhou, M., Bruijn, W., de, Brink, J., van den, de Vries , Ronald P, Birgit S Gruben, Henrissat, B., Cuotinho, P.M., Henrissat, Bernard, Kabel, Mirjam, Challen, Michael P, Wiebenga, A., Nadal, Marina, Coutinho, Pedro,, Patyshakuliyeva, A., Kabel, M., Mäkelä, Miia R, Makela, Miia R., Eastwood, Daniel C, van den Brink, J., Kabel, M.A., Wouter de Bruijn, Kabel, Mirjam, Burton, Kerry S, Gruben, Birgit S, Zhou, Miaomiao, Evy Battaglia, Coutinho, Pedro, M, Ad Wiebenga, Patyshakuliyeva, A, Challen, M.P., Gruppen , Harry, Annegret Kohler, Wiebenga, Ad, Baker, Adam, Aleksandrina Patyshakuliyeva, Eastwood, D.C., Bernard Henrissat, Vries, R.P., de, Kohler, A., Mäkelä, Miia, Baker, Adam R., Adam Baker, Francis Martin, Martin, Francis, de Bruijn, Wouter, Gruben, Birgit S., Burton, K.S., Coutinho, P.M., Burton, Kerry S., Coutinho, Pedro M, Ronald P de Vries, Baker, Adam, Jurak, Edita, Martin, F., Mirjam Kabel, Pedro M Coutinho, Daniel C Eastwood, Battaglia, E., Miia R Mäkelä, Edita Jurak, Harry Gruppen, Battaglia, Evy, Makela, M.R., Michael P Challen, de Bruijn, W., Kohler, Annegret, de Vries, R.P., Gruppen, H., Kerry S Burton, Nadal, M., Gruppen, Harry, Marina Nadal, van den Brink, Joost, Jurak, E., Miaomiao Zhou, Henrissat, Bernard, Challen, Michael P., Baker, A., Joost van den Brink   +83 more
core   +1 more source

Signaling pathways and mechanism of action of the extracellular superoxide dismutase, SOD3 [PDF]

, 2009
Reactive oxygen species (ROS) and especially hydrogen peroxide (H2O2) have been implicated in a multitude of cellular events ranging from pathogen eradication to finely tuned intracellular signal transduction under normal and pathological conditions.
Laatikainen, Lilja Elisa
core   +1 more source

Potential Activities of Freshwater Exo- and Endo-Acting Extracellular Peptidases in East Tennessee and the Pocono Mountains

Frontiers in Microbiology, 2018
Proteins constitute a particularly bioavailable subset of organic carbon and nitrogen in aquatic environments but must be hydrolyzed by extracellular enzymes prior to being metabolized by microorganisms.
Lauren Mullen, Malcolm X Shabazz High School Aquatic Biogeochemistry Team, Kim Boerrigter, Kim Boerrigter, Nicholas Ferriero, Jeff Rosalsky, Abigail van Buren Barrett, Patrick J. Murray, Andrew D. Steen   +8 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Trehalose Production Using Three Extracellular Enzymes Produced via One-Step Fermentation of an Engineered Bacillus subtilis Strain. [PDF]

Bioengineering (Basel), 2023
Sun X, Yang J, Fu X, Zhao X, Zhen J, Song H, Xu J, Zheng H, Bai W.   +8 more
europepmc   +1 more source