Results 91 to 100 of about 510,350 (297)

Characterization of two extracellular arabinanases in Lactobacillus crispatus

open access: yes, 2020
Extracellular glycosyl hydrolases are uncommon in lactobacilli and include amylases and fructosidases mediating starch and fructan utilization, respectively. Extracellular arabinanases have not been described in lactobacilli.
Li, Qing, Gänzle, Michael G.
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Studies on the regulation of extracellular collagenase production by vibrio alginolyticus

open access: yes, 1981
Bibliography: leaves 117-133.Vibrio alginolyticus synthesized extracellular collagenase in a highly aerated peptone medium at the late-exponential and early-stationary phases of growth.
Reid, Graham Charlton
core  

Syndecan-4 knockout leads to reduced extracellular transglutaminase-2 and protects against tubulointerstitial fibrosis

open access: yes, 2014
Transglutaminase type 2 (TG2) is an extracellular matrix crosslinking enzyme with a pivotal role in kidney fibrosis. The interaction of TG2 with the heparan sulfate proteoglycan syndecan-4 (Sdc4) regulates the cell surface trafficking, localization, and ...
Schroeder, N   +6 more
core   +1 more source

L‐proline and betaine inhibit extracellular enzymes mediated abeta 1‐42 aggregation, oxidative stress, and toxicity [PDF]

open access: yes, 2018
Extracellular amyloid plaques are characteristics of Alzheimer’s disease (AD). The amyloid plaques mainly consist of amyloid‐β (abeta) fragments. Extracellular biomolecules play a key role in abeta aggregation and subsequent plaque formation during AD ...
Mathumai Kanapathipillai   +5 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Extracellular Enzymes

open access: yes, 1984
Industrial enzymes that are almost invariably extracellular proteins, in that they are prepared from the fermentation broth rather than from the cells, are considered.
PRIEST, FERGUS G., Priest, F. G.
core  

Abiotic and biotic factors in the nutrient solution and filter skin (Schmutzdecke) of slow filters integrated to closed hydroponic greenhouse systems [PDF]

open access: yes, 2006
Rapid pathogen dispersal by circulating nutrient solutions in closed hydroponic systems poses a major threat to this production method. Slow filtration is very effective against important fungal pathogens such as Phytophthora cryptogea and Pythium ...
Furtner, Bernhard
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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