Results 91 to 100 of about 1,434,762 (289)

Linking microbial co‐occurrences to soil ecological processes across a woodland‐grassland ecotone

Ecology and Evolution, 2018
Ecotones between distinct ecosystems have been the focus of many studies as they offer valuable insights into key drivers of community structure and ecological processes that underpin function.
Samiran Banerjee, Peter H. Thrall, Andrew Bissett, Marcel G. A. van derHeijden, Alan E. Richardson   +4 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]

, 2013
Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
E. Buzás, A. Falus, Á. Kittel, Buzás, E., Kittel, Ágnes, Falus, A.   +5 more
core   +1 more source

Extracellular Enzymes of Invertebrate Origin

, 2018
Extracellular enzymes contribute substantially to the remineralisation of organic matter in aquatic systems. It has been suggested that marine invertebrates release endogenous enzymes through activities such as feeding, but the importance of this ...
Böök, Imke M.
core   +1 more source

Epigenetic modulation of fungal pathogens: a focus on Magnaporthe oryzae

Frontiers in Microbiology
Epigenetics has emerged as a potent field of study for understanding the factors influencing the effectiveness of human disease treatments and for identifying alternations induced by pathogens in host plants. However, there has been a paucity of research
Hafiz Muhammad Usman Aslam, Hafiz Muhammad Usman Aslam, Mohamad Chikh-Ali, Xin-Gen Zhou, Shouan Zhang, Steven Harris, Ashok K. Chanda, Hasan Riaz, Akhtar Hameed, Saba Aslam, Nabil Killiny   +10 more
doaj   +1 more source

The endocytosis gene END3 is essential for the glucose-induced rapid decline of small vesicles in the extracellular fraction in Saccharomyces cerevisiae

Journal of Extracellular Vesicles, 2014
Background: Protein secretion is a fundamental process in all living cells. Gluconeogenic enzymes are secreted when Saccharomyces cerevisiae are grown in media containing low glucose.
Bennett J. Giardina, Kathryn Stein, Hui-Ling Chiang   +2 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

TYPES OF EXTRACELLULAR ENZYMES SECRETED BY FUNGI [PDF]

Objective: This study aims to review the diversity and significance of extracellular enzymes secreted by fungi, with a focus on their ecological functions and industrial applications.
Badr, Sanaa Qasem
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source