Results 11 to 20 of about 334,235 (263)

Small non-coding RNA landscape of extracellular vesicles from a post-traumatic model of equine osteoarthritis

Frontiers in Veterinary Science, 2022
Extracellular vesicles comprise an as yet inadequately investigated intercellular communication pathway in the field of early osteoarthritis. We hypothesised that the small non-coding RNA expression pattern in synovial fluid and plasma would change ...
James R. Anderson, Stine Jacobsen, Marie Walters, Louise Bundgaard, Andreas Diendorfer, Matthias Hackl, Emily J. Clarke, Victoria James, Mandy J. Peffers   +8 more
doaj   +1 more source

Messenger roles of extracellular vesicles during fertilization of gametes, development and implantation: Recent advances

Frontiers in Cell and Developmental Biology, 2023
Extracellular vesicles (EVs) have become a research hotspot in recent years because they act as messengers between cells in the physiological and pathological processes of the human body.
Weisen Fan, Yinghua Qi, Yaqian Wang, Huiting Yan, Xuan Li, Yingjie Zhang   +5 more
doaj   +1 more source

The extracellular volume status predicts body fluid response to SGLT2 inhibitor dapagliflozin in diabetic kidney disease

Diabetology & Metabolic Syndrome, 2020
Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors are an antihyperglycemic drug with diuretic action. We recently reported that the SGLT2 inhibitor dapagliflozin ameliorates extracellular volume expansion with a mild increase in urine volume ...
Ken Ohara, Takahiro Masuda, Masato Morinari, Mari Okada, Atsushi Miki, Saki Nakagawa, Takuya Murakami, Kentaro Oka, Maki Asakura, Yasuharu Miyazawa, Akito Maeshima, Tetsu Akimoto, Osamu Saito, Daisuke Nagata   +13 more
doaj   +1 more source

Temporal extracellular vesicle protein changes following intraarticular treatment with integrin α10β1-selected mesenchymal stem cells in equine osteoarthritis

Frontiers in Veterinary Science, 2022
IntroductionEquine osteoarthritis (OA) is a heterogeneous, degenerative disease of the musculoskeletal system with multifactorial causation, characterized by a joint metabolic imbalance.
Emily J. Clarke, Emily Johnson, Eva Caamaño Gutierrez, Camilla Andersen, Lise C. Berg, Rosalind E. Jenkins, Casper Lindegaard, Kristina Uvebrant, Evy Lundgren-Åkerlund, Agnieszka Turlo, Victoria James, Stine Jacobsen, Mandy J. Peffers   +12 more
doaj   +1 more source

The effect of preoperative fasting on the water sectors of the body in the perioperative period in children

Вестник анестезиологии и реаниматологии
Introduction. Avoiding solid foods and liquids before surgery is a common practice in elective surgery in pediatric, however, there is a risk of dehydration.The objective was to assess the distribution of fluid across the water sectors of the body in ...
Yu. S. Aleksandrovich, K. V. Pshenisnov, Sh. Sh. Shorakhmedov, G. P. Tihova   +3 more
doaj   +1 more source

Machine Learning Model Based on Transthoracic Bioimpedance and Heart Rate Variability for Lung Fluid Accumulation Detection: Prospective Clinical Study

JMIR Medical Informatics, 2020
BackgroundAccumulation of excess body fluid and autonomic dysregulation are clinically important characteristics of acute decompensated heart failure.
Reljin, Natasa, Posada-Quintero, Hugo F, Eaton-Robb, Caitlin, Binici, Sophia, Ensom, Emily, Ding, Eric, Hayes, Anna, Riistama, Jarno, Darling, Chad, McManus, David, Chon, Ki H   +10 more
doaj   +1 more source

Deep medullary vein dysfunction is associated with cerebral microbleeds in cerebral small vessel disease

Frontiers in Human Neuroscience
ObjectiveThis study investigated the association between deep medullary vein (DMV) dysfunction and the development of cerebral microbleeds (CMB) in patients with cerebral small vessel disease (CSVD), with a particular focus on the contribution of ...
Haiyuan Lan, Xinjun Lei, Zhihua Xu, Jie Yu, Huimei Wang   +4 more
doaj   +1 more source

An Advanced Pneumatic Compression Therapy System Improves Leg Volume and Fluid, Adipose Tissue Thickness, Symptoms, and Quality of Life and Reduces Risk of Lymphedema in Women with Lipedema

Life
Lipedema is a painful disease of subcutaneous adipose tissue (SAT) in women. This study determined whether an advanced pneumatic compression device (APCD) improved lipedema SAT depth, swelling, and pain.
Karen L. Herbst, Carlos Zelaya, Marianne Sommerville, Tatiana Zimmerman, Lindy McHutchison   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Oral extracellular vesicles in early pregnancy can identify patients at risk of developing gestational diabetes mellitus.

PLoS ONE, 2019
AimTo isolate and characterize oral extracellular vesicles from gingival crevicular fluid at 11-14 weeks and evaluate their capacity to identify patients at risk of developing gestational diabetes mellitus.MethodsA case-control study was conducted ...
Lara J Monteiro, Manuel Varas-Godoy, Max Monckeberg, Ornella Realini, Marcela Hernández, Gregory Rice, Roberto Romero, José F Saavedra, Sebastián E Illanes, Alejandra Chaparro   +9 more
doaj   +1 more source