Results 61 to 70 of about 321,051 (313)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Wearable and noninvasive monitoring of fluid shifts: A pilot study assessing a novel bioimpedance sensor during lower body negative pressure

Physiological Reports
Fluid extravasation is a prominent feature of several disease processes in acute and critical illness. Bioimpedance at frequencies representing extracellular and total resistance offers an opportunity to monitor fluid shifts. The aim of the present study
Lars Øivind Høiseth, Frida Bremnes, Sigve Nyvik Aas, Anne Thorud, Harald Noddeland   +4 more
doaj   +1 more source

Wound Fluid Extracellular Microvesicles: A Potential Innovative Biomarker for Wound Healing

Plastic and Reconstructive Surgery, Global Open
Background:. Extracellular vesicles, or microvesicles, are a large family of membrane-bound fluid-filled sacs that cells release into the extracellular environment.
Walid Mari, MD, MSc, Sara Younes, MD, MSc, Erin Sheehan, BS, Terry L Oroszi, MS, EdD, David R Cool, PhD, Rajab Suliman, PhD, Richard Simman, MD, FACS, FACCWS   +6 more
doaj   +1 more source

Lipidome profiling of human and equine neutrophil-derived extracellular vesicles and their potential contribution to the ensemble of synovial fluid-derived extracellular vesicles during joint inflammation [PDF]

, 2023
Laura Varela, Sanne Mol, Esther W. Taanman-Kueter, Sarah Ryan, Leonie S. Taams, Esther C. de Jong, P. René van Weeren, Chris H.A. van de Lest, Marca H. M. Wauben   +8 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid promotes the nodules growth through FGF14 in patients with lung cancers [PDF]

, 2023
Jing Huang, Ming Ding, Yuan Lu, Xu Lu, Yu Zhang, Shuhua Han, Xiaoli Zhu, Yiping Li, Pingsheng Chen   +8 more
openalex   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Hydration Status Is Associated with Aortic Stiffness, but Not with Peripheral Arterial Stiffness, in Chronically Hemodialysed Patients

International Journal of Nephrology, 2015
Background. Adequate fluid management could be essential to minimize high arterial stiffness observed in chronically hemodialyzed patients (CHP). Aim. To determine the association between body fluid status and central and peripheral arterial stiffness ...
Daniel Bia, Cintia Galli, Rodolfo Valtuille, Yanina Zócalo, Sandra A. Wray, Ricardo L. Armentano, Edmundo I. Cabrera Fischer   +6 more
doaj   +1 more source

Measurement of extracellular fluid compartment volume using inulin:

مجلة كلية الطب, 2008
Background: There is a need to find methods to assess the size of the extracellular fluid (ECF) volume without involving radioactive tracers. For this purpose, the simple delusion method was used to measure the ECF in rabbits and the inulin which is a ...
Ghassan T. Al-Ani
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source