Results 71 to 80 of about 2,888,104 (308)
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr+5 more
wiley +1 more source
Osmotic pressure‐induced calcium response states
Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao+2 more
wiley +1 more source
AN ANTIDIURETIC MECHANISM NOT REGULATED BY EXTRACELLULAR FLUID TONICITY 12 [PDF]
Alexander Leaf, Audley R. Mamby
openalex +1 more source
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi+5 more
wiley +1 more source
DETERMINATION OF THE VOLUME OF THE EXTRACELLULAR FLUID OF THE BODY WITH RADIOACTIVE SODIUM [PDF]
Nolan L. Kaltreider+3 more
openalex +1 more source
L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
M. Norman+9 more
semanticscholar +1 more source
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu+6 more
wiley +1 more source
Hydrostatic Pressure Gradient Ultrafiltration Device: A Novel Approach for Extracellular Fluid Removal. [PDF]
Feld Y, Hanani N, Costanzo MR.
europepmc +1 more source
The total intracellular concentration of mammalian tissues compared with that of the extracellular fluid [PDF]
E. J. Conway, Joel McCormack
openalex +1 more source
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior+5 more
wiley +1 more source