Results 211 to 220 of about 706,858 (272)

Ischemic Myocardium Targeting Peptide‐Guided Nanobubbles for Multimodal Imaging and Treatment of Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu, Ziwei Pang, Jing Zhao, Jingyi Xue, Hsuan Lo, Tiancheng Gu, Ping Zhang, Jiawei Tian, Guo‐Qing Du   +8 more
wiley   +1 more source

The effects of extracellular matrix-degrading enzymes polymorphisms on intervertebral disc degeneration. [PDF]

JOR Spine
Zhao D, Dou YX, Zeng LF, Han YH, Lin FZ, Xu NJ, Liu J, Zeng YP.   +7 more
europepmc   +1 more source

Bioprinting Perfusable and Vascularized Skeletal Muscle Flaps for the Treatment of Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss (VML) due to trauma or surgery, often leads to physical impairments. Traditional treatments rely on autologous flaps, limited by muscle availability often leading to donor site morbidity. This study presents multimodal bioprinting as an innovative approach for fabricating vascularized muscle flaps with 3D‐printed macrovessels ...
Eliana O. Fischer, Anna Tsukerman, Majd Machour, Margarita Shuhmaher, Asaf Silverstein, Maya Yaakov, Orit Bar‐Am, Lior Debbi, Shulamit Levenberg   +8 more
wiley   +1 more source

Implication of the Extracellular Matrix in Metastatic Tumor Cell Dormancy. [PDF]

Cancers (Basel)
Redoute-Timonnier C, Auguste P.
europepmc   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Preclinical extracellular matrix-based treatment strategies for myocardial infarction: a systematic review and meta-analysis. [PDF]

Commun Med (Lond)
van der Pol A, Peters MC, Jorba I, Smits AM, van der Kaaij NP, Goumans MJ, Wever KE, Bouten CVC.   +7 more
europepmc   +1 more source

Enhanced PDMS Functionalization for Organ‐on‐a‐Chip Platforms Using Ozone and Sulfo‐SANPAH: A Simple Approach for Biomimetic Long‐Term Cell Cultures

Advanced Healthcare Materials, EarlyView.
The use of organ‐on‐a‐chip (OOC) microfluidic platforms is expanding in biomedical research. While this emerging technology is becoming increasingly accessible, the stability of long‐term functional cultures remains a critical challenge to address. This study presents a straightforward, one‐step method for the functionalization of polydimethylsiloxane ...
Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Alyssa Shapiro, Lazaro Huerta, Mathieu Hautefeuille, Marina Macías‐Silva, Daniel Pérez‐Calixto, Genaro Vázquez‐Victorio   +7 more
wiley   +1 more source

Loss of PRICKLE1 leads to subfertility, aberrant extracellular matrix and abnormal myometrial architecture in mice. [PDF]

Reproduction
Roberts ER, Ganeshkumar S, Gunewardena S, Chennathukuzhi V.   +3 more
europepmc   +1 more source

Lycium‐Barbarum Polysaccharide‐Loaded Dual‐Crosslinked Rigid Hydrogel Enhances Bone Healing in Diabetic Bone Defects by Scavenging Reactive Oxygen Species

Advanced Healthcare Materials, EarlyView.
A novel hydrogel (HLBP) incorporating natural polysaccharides from goji berries is developed to enhance diabetic bone defect healing. The hydrogel efficiently scavenges ROS, improves osteogenic differentiation, and promotes in vivo bone regeneration. This strategy offers a biocompatible and localized approach, overcoming the challenges of traditional ...
Wenjie Zhong, Wenao Liao, Lingcong Xu, Niezhenghao He, Ke Xu, Caiyuan Liu, Fei Wang, Wei Zhang, Jiang Hu, Haowen Cui   +9 more
wiley   +1 more source

Neurocircuit regeneration by extracellular matrix reprogramming. [PDF]

Neural Regen Res
Su S, Levasseur IN, Alonge KM.
europepmc   +1 more source